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Database: UniProt
Entry: M3WFA2_FELCA
LinkDB: M3WFA2_FELCA
Original site: M3WFA2_FELCA 
ID   M3WFA2_FELCA            Unreviewed;      1288 AA.
AC   M3WFA2;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   28-MAR-2018, entry version 34.
DE   SubName: Full=5-oxoprolinase, ATP-hydrolysing {ECO:0000313|Ensembl:ENSFCAP00000010718};
GN   Name=OPLAH {ECO:0000313|Ensembl:ENSFCAP00000010718};
OS   Felis catus (Cat) (Felis silvestris catus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
OC   Felinae; Felis.
OX   NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000010718, ECO:0000313|Proteomes:UP000011712};
RN   [1] {ECO:0000313|Ensembl:ENSFCAP00000010718, ECO:0000313|Proteomes:UP000011712}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010718,
RC   ECO:0000313|Proteomes:UP000011712};
RX   PubMed=17975172; DOI=10.1101/gr.6380007;
RA   Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA   Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
RA   Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
RA   Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
RA   Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
RT   "Initial sequence and comparative analysis of the cat genome.";
RL   Genome Res. 17:1675-1689(2007).
RN   [2] {ECO:0000313|Ensembl:ENSFCAP00000010718}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010718};
RA   Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT   "Sequence assembly of the Felis catus genome version 6.2.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSFCAP00000010718}
RP   IDENTIFICATION.
RC   STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010718};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
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DR   EMBL; AANG03352686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_004000216.1; XM_004000167.3.
DR   STRING; 9685.ENSFCAP00000010718; -.
DR   Ensembl; ENSFCAT00000011546; ENSFCAP00000010718; ENSFCAG00000011543.
DR   GeneID; 101100620; -.
DR   KEGG; fca:101100620; -.
DR   CTD; 26873; -.
DR   eggNOG; KOG1939; Eukaryota.
DR   eggNOG; COG0145; LUCA.
DR   eggNOG; COG0146; LUCA.
DR   GeneTree; ENSGT00390000013463; -.
DR   InParanoid; M3WFA2; -.
DR   KO; K01469; -.
DR   OMA; PLTVTDC; -.
DR   OrthoDB; EOG091G00VX; -.
DR   Proteomes; UP000011712; Chromosome F2.
DR   Bgee; ENSFCAG00000011543; -.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IBA:GO_Central.
DR   GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011712};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT   DOMAIN       10    212       Hydant_A_N. {ECO:0000259|Pfam:PF05378}.
FT   DOMAIN      231    530       Hydantoinase_A. {ECO:0000259|Pfam:
FT                                PF01968}.
FT   DOMAIN      734   1256       Hydantoinase_B. {ECO:0000259|Pfam:
FT                                PF02538}.
FT   COILED      544    564       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1288 AA;  137730 MW;  AF78188B265C5527 CRC64;
     MGSPEGRFHF AIDRGGTFTD VFAQCPGGQV RVLKLLSEDP ANYADAPTEG IRRILEQEGG
     VVLPRDQPLD TSRIASIRMG TTVATNALLE RRGERVALLV TRGFRDLLHV GTQAREDLFD
     LAVPMPEVLY EEVLEVDERV VLYRGEPGAG TPVKGRTGDL LEVRQPVDLG ALRGKLEALL
     SRGVRSLAVV LMHSYTWAQH EQQVGALARE LGFTHVALSS DTMPMVRIVP RGHTACADAY
     LTPTIRRYVQ GFRRGFRGQL KDVQVLFMRS DGGLAPMESF SGSRAVLSGP AGGVVGYSAT
     TYRVEGGQPV IGFDMGGTST DVSRYAGEFE HVFEASTAGV TLQAPQLDIN TVAAGGGSRL
     FFRSGLFVVG PESAGAHPGP ACYRKGGPVT VTDANLVLGR LLPASFPCIF GPGEDQPLSS
     EASRKALETV AAEVNSFLTN GPCPASPLSL EEVAMGFVRV ANEAMCRPIR ALTQARGHDP
     SAHVLACFGG AGGQHACAIA RALGMDTVHV HRHSGLLSAL GLALADVVHE AQEPCSLPYA
     PETFVQLDQR LSRLEEQCVD ALRAQGFPRS QISTESFLHL RYQGTDCALM VSAHRHPAAA
     RSPRAGDFGA AFVERYMREF GFVIPERPVV VDDVRVRGTG RSGLRLEDVP RAQTGPPRID
     KMTQCYFEGG YQETPVYLLG ELAYGHKLQG PCLIIDSNST ILVEPGCQAE VTDTGDIRIS
     VGAEVPSLVG AQLDPIHLSI FSHRFMSIAE QMGRILQRTA ISTNIKERLD FSCALFGPDG
     GLVSNAPHIP VHLGAMQETV QFQIQHLGAD LHPGDVLLSN HPSAGGSHLP DLTVITPVFW
     PGQTRPVFYV ASRGHHADIG GITPGSMPPH STTLQQEGAV FLSFKLVQGG VFQEEAVTEA
     LQAPGKIPGC SGTRNLHDNL SDLRAQVAAN QKGIQLVGEL IGQYGLDVVQ AYMGHIQANA
     ELAVRDMLRA FGTSRQARGL PLEVSAEDHM DDGSPIRLRV QINLSQGSAV FDFSGTGPEV
     FGNLNAPRAI TLSALIYCLR CLVGRDIPLN QGCLAPVRVV IPRGCILDPS PEAAVVGGNV
     LTSQRVVDVI LGAFGACAAS QGCMNNVTLG NAHMGYYETV AGGAGAGPGW HGRSGVHSHM
     TNTRITDPEI LESRYPVILR RFELRQGSGG RGRFRGGDGV VRELLFREEA LLSVLTERRA
     FRPYGLHGGE PGARGLNLLI RKDGRTVNLG GKTSVPVFPG DVFCLHTPGG GGYGDPEDPA
     PPPGSPPQPP AFSERGSVYE YRRAQEAV
//
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