ID M3WI25_FELCA Unreviewed; 405 AA.
AC M3WI25;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Beta-arrestin-2 {ECO:0000256|ARBA:ARBA00040110};
DE AltName: Full=Arrestin beta-2 {ECO:0000256|ARBA:ARBA00042805};
GN Name=ARRB2 {ECO:0000313|Ensembl:ENSFCAP00000012079.5,
GN ECO:0000313|VGNC:VGNC:97355};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000012079.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000012079.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012079.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000012079.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012079.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000012079.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012079.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR EMBL; AANG04000740; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WI25; -.
DR Ensembl; ENSFCAT00000013026.5; ENSFCAP00000012079.5; ENSFCAG00000013022.6.
DR VGNC; VGNC:97355; ARRB2.
DR eggNOG; KOG3865; Eukaryota.
DR GeneTree; ENSGT00950000182887; -.
DR HOGENOM; CLU_033484_1_1_1; -.
DR Proteomes; UP000011712; Chromosome E1.
DR Bgee; ENSFCAG00000013022; Expressed in spleen and 9 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.640; -; 1.
DR Gene3D; 2.60.40.840; -; 1.
DR InterPro; IPR000698; Arrestin.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR017864; Arrestin_CS.
DR InterPro; IPR014753; Arrestin_N.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11792; ARRESTIN; 1.
DR PANTHER; PTHR11792:SF20; BETA-ARRESTIN-2; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR PRINTS; PR00309; ARRESTIN.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
DR PROSITE; PS00295; ARRESTINS; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 179..334
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
SQ SEQUENCE 405 AA; 45570 MW; 327AC55BF3F927C8 CRC64;
MGEKPGTRVF KKSSPNCKLT VYLGKRDFVD HLDRVDPVVF VTLTCAFRYG REDLDVLGLS
FRKDLFIATY QAFPPMPNPP RPPTRLQDRL LRKLGQHAHP FFFTIPQNLP CSVTLQPGPE
DTGKACGVDF EIRAFCAKSL EEKSHKRNSV RLVIRKVQFA PEKPGPQPSA ETTRHFLMSD
RSLHLEASLD KELYYHGEPL NVNVHVTNNS TKTVKKIKVS VRQYADICLF STAQYKCPVA
QIEQDDQVSP SSTFCKVYTI TPLLSDNREK RGLALDGKLK HEDTNLASST IVKEGANKEV
LGILVSYRVK VKLVVARGGD VSVELPFVLM HPKPHDHITL PRPQTAPTHP PPLLASAAPE
TDAPVDTNLI EFDTNYATDD DIVFEDFARL RLKGMKDEDY EDQFC
//
