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Database: UniProt
Entry: M3WTQ5_FELCA
LinkDB: M3WTQ5_FELCA
Original site: M3WTQ5_FELCA 
ID   M3WTQ5_FELCA            Unreviewed;       508 AA.
AC   M3WTQ5;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 2.
DT   28-MAR-2018, entry version 47.
DE   SubName: Full=Cation channel sperm associated 2 {ECO:0000313|Ensembl:ENSFCAP00000017741};
GN   Name=CATSPER2 {ECO:0000313|Ensembl:ENSFCAP00000017741};
OS   Felis catus (Cat) (Felis silvestris catus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
OC   Felinae; Felis.
OX   NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000017741, ECO:0000313|Proteomes:UP000011712};
RN   [1] {ECO:0000313|Ensembl:ENSFCAP00000017741, ECO:0000313|Proteomes:UP000011712}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000017741,
RC   ECO:0000313|Proteomes:UP000011712};
RX   PubMed=17975172; DOI=10.1101/gr.6380007;
RA   Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA   Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
RA   Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
RA   Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
RA   Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
RT   "Initial sequence and comparative analysis of the cat genome.";
RL   Genome Res. 17:1675-1689(2007).
RN   [2] {ECO:0000313|Ensembl:ENSFCAP00000017741, ECO:0000313|Proteomes:UP000011712}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000017741,
RC   ECO:0000313|Proteomes:UP000011712};
RA   Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT   "Sequence assembly of the Felis catus genome version 6.2.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSFCAP00000017741}
RP   IDENTIFICATION.
RC   STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000017741};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
RN   [4] {ECO:0000313|Ensembl:ENSFCAP00000035076}
RP   IDENTIFICATION.
RC   STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000035076};
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
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DR   EMBL; AANG03030808; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9685.ENSFCAP00000017741; -.
DR   Ensembl; ENSFCAT00000025567; ENSFCAP00000017741; ENSFCAG00000025930.
DR   Ensembl; ENSFCAT00000032971; ENSFCAP00000035076; ENSFCAG00000025930.
DR   CTD; 117155; -.
DR   eggNOG; ENOG410INF6; Eukaryota.
DR   eggNOG; ENOG4111GC6; LUCA.
DR   GeneTree; ENSGT00910000144338; -.
DR   InParanoid; M3WTQ5; -.
DR   OMA; TLEVAAW; -.
DR   OrthoDB; EOG091G0I4O; -.
DR   Proteomes; UP000011712; Chromosome B3.
DR   Bgee; ENSFCAG00000025930; -.
DR   GO; GO:0036128; C:CatSper complex; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005227; F:calcium activated cation channel activity; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IBA:GO_Central.
DR   GO; GO:0030317; P:flagellated sperm motility; IEA:InterPro.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   GO; GO:0019228; P:neuronal action potential; IBA:GO_Central.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR028747; CatSper2.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR10037:SF189; PTHR10037:SF189; 2.
DR   Pfam; PF00520; Ion_trans; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011712};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    100    127       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    148    173       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    179    199       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    244    263       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    283    301       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    321    341       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      108    349       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      341    361       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   508 AA;  59872 MW;  C25B6A6312CA3C59 CRC64;
     MATSHPAGHV QLPRADAIRS RLIDTFSLIE HLQGLSQAVP RHTIREILDP SGQKKLMLGD
     QHQLVRFSIK PRHVERITRG RRLMSRLHVR YSQRPPLSLW AGWVLECPLF TNFIIFLIFL
     NTIVLMVEIE LLESSNTKLW SLKLSLEVAA WFILLIFILE ILLMWISSFF LFWKNAWNVF
     DFVVTILSLL PEVVVLVGVT GQSVWLQLLR ICRVLRSLKL FARFRQIRVI ILALMRALKS
     MTFLLMLLLI FFYIFAVTGV YFFEDYTRST RQDLEYHMFF SDLLNSLVTV FILFTMDHWY
     ALLQDTWKVP EVSRTFSSIY VILWLLLGSI IFRNIIVAMM VTNFQNIRNE LNEEMTHLEV
     QHKADIFKRQ IIQRRQNLSP EALRSSLSKM DARDASQQRE SLELSTAFEE ESKHSADEEG
     SRASVSKTKE SLSKMKKYLD SIGQLDWETH VHQNLPGLME MDQDDRVVWP RDSLFRYFEL
     LEKLQYNLEE RKRLQEFAVQ ALMNFEDK
//
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