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Database: UniProt
Entry: M3XDS9_FELCA
LinkDB: M3XDS9_FELCA
Original site: M3XDS9_FELCA 
ID   M3XDS9_FELCA            Unreviewed;       655 AA.
AC   M3XDS9;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-SEP-2017, entry version 38.
DE   SubName: Full=Potassium voltage-gated channel subfamily A member 4 {ECO:0000313|Ensembl:ENSFCAP00000024785};
GN   Name=KCNA4 {ECO:0000313|Ensembl:ENSFCAP00000024785};
OS   Felis catus (Cat) (Felis silvestris catus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
OC   Felinae; Felis.
OX   NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000024785, ECO:0000313|Proteomes:UP000011712};
RN   [1] {ECO:0000313|Ensembl:ENSFCAP00000024785, ECO:0000313|Proteomes:UP000011712}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024785,
RC   ECO:0000313|Proteomes:UP000011712};
RX   PubMed=17975172; DOI=10.1101/gr.6380007;
RA   Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA   Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
RA   Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
RA   Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
RA   Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
RT   "Initial sequence and comparative analysis of the cat genome.";
RL   Genome Res. 17:1675-1689(2007).
RN   [2] {ECO:0000313|Ensembl:ENSFCAP00000024785}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024785};
RA   Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT   "Sequence assembly of the Felis catus genome version 6.2.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSFCAP00000024785}
RP   IDENTIFICATION.
RC   STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000024785};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSFCAP00000024785}.
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DR   EMBL; AANG02009856; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9685.ENSFCAP00000024785; -.
DR   Ensembl; ENSFCAT00000026470; ENSFCAP00000024785; ENSFCAG00000031951.
DR   eggNOG; KOG1545; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00760000118846; -.
DR   InParanoid; M3XDS9; -.
DR   OMA; RQRPEKK; -.
DR   OrthoDB; EOG091G10NU; -.
DR   Proteomes; UP000011712; Chromosome D1.
DR   Bgee; ENSFCAG00000031951; -.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:GO_Central.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   Gene3D; 1.20.5.600; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR   InterPro; IPR020467; K_chnl_volt-dep_Kv1.4.
DR   InterPro; IPR012897; K_chnl_volt-dep_Kv1.4_TID.
DR   InterPro; IPR011333; SKP1/BTB/POZ.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF07941; K_channel_TID; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01511; KV14CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01496; SHAKERCHANEL.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011712};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00091688}.
FT   TRANSMEM    310    328       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    480    501       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    541    562       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      178    278       BTB. {ECO:0000259|SMART:SM00225}.
FT   COILED      111    139       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   655 AA;  73556 MW;  AC7EEC2C99B971A5 CRC64;
     MEVAMVSAES SGCNSHMPYG YAAQARARER ERLAHSRAAA AAAVAAATAA VEGSGGSGGS
     SHHHHQSRGA CTSHDPQGSR GSRRRRRQRP EKRRVHHRQS SFPHCSDLMP SGSEEKILRE
     LSEEEEEEEE EEEEEEEEGR FYYSEDDHGD ECSYTDLLPQ DDGGGGGYSS VRYSDCCERV
     VINVSGLRFE TQMKTLAQFP ETLLGDPEKR TQYFDPLRNE YFFDRNRPSF DAILYYYQSG
     GRLKRPVNVP FDIFTEEVKF YQLGEEALLK FREDEGFVRE EEDRALPENE FKKQIWLLFE
     YPESSSPARG IAIVSVLVIL ISIVIFCLET LPEFRDDRDL IMALSAGGHS GLLNDTSAPH
     LENSGHTIFN DPFFIVETVC IVWFSFEFVV RCFACPSQAL FFKNIMNIID IVSILPYFIT
     LGTDLAQQQG GGNGQQQQAM SFAILRIIRL VRVFRIFKLS RHSKGLQILG HTLRASMREL
     GLLIFFLFIG VILFSSAVYF AEADEPTTHF QSIPDAFWWA VVTMTTVGYG DMKPITVGGK
     IVGSLCAIAG VLTIALPVPV IVSNFNYFYH RETENEEQTQ LTQNAVSCPY LPSNLLKKFR
     SSTSSSLGDK SEYLEMEEGV KESLCAKEEK CQGKGDDSET DKNNCSNAKA VETDV
//
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