ID M3XH79_LATCH Unreviewed; 484 AA.
AC M3XH79;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Nectin cell adhesion molecule 2 {ECO:0000313|Ensembl:ENSLACP00000022085.1};
GN Name=NECTIN2 {ECO:0000313|Ensembl:ENSLACP00000022085.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000022085.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000022085.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01099542; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01099543; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01099544; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01099545; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3XH79; -.
DR Ensembl; ENSLACT00000026463.1; ENSLACP00000022085.1; ENSLACG00000014048.2.
DR GeneTree; ENSGT00940000161167; -.
DR HOGENOM; CLU_029618_0_1_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000014048; Expressed in pectoral fin and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR47387; NECTIN-2; 1.
DR PANTHER; PTHR47387:SF1; NECTIN-2; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..484
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004043395"
FT TRANSMEM 343..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..137
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 142..233
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 240..327
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 373..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 484 AA; 54052 MW; 7D7E5D54C44E7F6D CRC64;
MRLCVRIAIL VAIGSCWLCA QAQRVKVKPE VSGYEGQEVT MQCTFADANQ DTKLTQNSWA
KMSADGEKET VAVYNPQFGA NYPLPSFQNR IKFRVQEKYP RDATLIISPL KIGDEGTYVC
EFATYPHGNE EEEVKLDVLV KPTNDAKAVP VDAGESMVTV ATCISANGKP ASEITWRSEL
EGNYTNTEET GADGKITVTS WYKVVPTSKV NGMKIACEVR HKTTGSPETF PVHLSVQYPP
EVRIQGYDDN WYRNRKDVQL TCEADANPPV TKYEWKLLDR TFPPSVTVGG VNEEVLHVEQ
VDDDLNATFI CQATNALGIG DTKLKVFVRD SPVPDSTVKT GGIIGGIIAA IVVLAVLVTA
ILIWKRQQKN KTFGKDEEFD NPPNYKPPPP QRKVEDTDLD EKTPAEESIP LRTTYFETST
VEDPTYTEGS KNYDAPNDFE EEDDLKVTLP TQDDYREQVN PIYNNLSYPL HDDKESFVSE
AMYV
//
