ID M3XQ52_MUSPF Unreviewed; 577 AA.
AC M3XQ52;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM7 {ECO:0000313|RefSeq:XP_004780268.1};
DE SubName: Full=Tripartite motif containing 7 {ECO:0000313|Ensembl:ENSMPUP00000001202.1};
GN Name=TRIM7 {ECO:0000313|Ensembl:ENSMPUP00000001202.1,
GN ECO:0000313|RefSeq:XP_004780268.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000001202.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000001202.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004780268.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004780268.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AEYP01099522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004780268.1; XM_004780211.3.
DR STRING; 9669.ENSMPUP00000001202; -.
DR Ensembl; ENSMPUT00000001228.1; ENSMPUP00000001202.1; ENSMPUG00000001212.1.
DR GeneID; 101691971; -.
DR KEGG; mpuf:101691971; -.
DR CTD; 81786; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT01030000234669; -.
DR HOGENOM; CLU_013137_0_3_1; -.
DR OMA; DMKMHIC; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0140374; P:antiviral innate immune response; IEA:Ensembl.
DR CDD; cd19762; Bbox2_TRIM7-like; 1.
DR CDD; cd16594; RING-HC_TRIM7-like_C-IV; 1.
DR CDD; cd13740; SPRY_PRY_TRIM7; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF689; E3 UBIQUITIN-PROTEIN LIGASE TRIM7; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 100..152
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 191..232
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 390..577
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 240..281
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 14..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 63771 MW; CA8C8764FD7B7E44 CRC64;
MVWPAHRALA SVSLPGRASS QLRSPPVRLQ PRPSSPSGCS EAGPGQPTRN RVLSGPSTSP
APPGSGTPRE RMAAVGPRTD PGAGAEALAL AAELQGETTC SICLEMFREP VSVECGHSFC
RSCIARCWER PAVGAPAASR PLPGPLPCPQ CREPVRPGQL RPNRQLASVT TLLRRFSLPA
AAPGERGPAQ AAAAGCVQHG EPLKLYCQDD GRAICVVCDR AREHRAHAVL PLDEAVQEAK
ELLESRLKVL KKDLEDYEVF RSTEEKESKE LLKQMAAERE KVSAEFQALR AFLVEQEGRL
LGRLEELSRE VTQKQNENIA QLGGEITHLS KLSSQIQETS RKPDLDFLQE FRNTLRRCNN
VPGPKPTTVS SEMKNKVWNV SLKTFVLKGL LKKFKEDLRG ELEKEEKVEL TLDPDTANPR
LILSLDLKSV RLGQRAQDVP CHPCRFDTNT RVLASCGFSS GRHHWEVEVG SKDGWAFGVA
RESVRRKGLT PFTPEEGVWA LQLNSGKYWA VTSPERTPLS CGQLSRVRVA LDLEVGAVSF
YAAEDMRHLY TFRVNFHERV FPLFSVCSTG TYLRIWP
//
