ID M3Y9E1_MUSPF Unreviewed; 2191 AA.
AC M3Y9E1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Death inducer-obliterator 1 {ECO:0000313|Ensembl:ENSMPUP00000007948.1};
GN Name=DIDO1 {ECO:0000313|Ensembl:ENSMPUP00000007948.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000007948.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000007948.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEYP01050482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01050483; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9669.ENSMPUP00000007948; -.
DR Ensembl; ENSMPUT00000008073.1; ENSMPUP00000007948.1; ENSMPUG00000008006.1.
DR eggNOG; KOG1632; Eukaryota.
DR eggNOG; KOG1634; Eukaryota.
DR GeneTree; ENSGT00940000155532; -.
DR HOGENOM; CLU_000673_1_0_1; -.
DR InParanoid; M3Y9E1; -.
DR OMA; HPNQFDG; -.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd15639; PHD_DIDO1_like; 1.
DR CDD; cd21547; SPOC_DIDO1-like; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR033082; DIDO1_PHD.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11477:SF13; DEATH-INDUCER OBLITERATOR 1; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 264..320
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 664..784
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 1..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 853..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 957..987
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1197..1430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1442..1506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1518..2191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..90
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..253
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..792
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..880
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 909..925
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 957..971
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1197..1214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1267
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1300..1316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1389..1420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1479..1495
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1562..1586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1650..1664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1822..1841
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1884..1908
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1950..2003
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2004..2179
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2191 AA; 236243 MW; ED97C7E15143329E CRC64;
MDEKGDPSNE EVPKAIKPTS KEFRKTWGFR RTTIAKREGA GDADLDAPEP QPQQQQSLSL
RRSGRQPKRT ERVEEFLTTV RRRGRKNAPV SLEDSGEAAS CAVTDVETAS EGSVESTSEG
KGGPPSGSVG DKERPAASVK AKGGEDEDDT SDSDSDGLTL KELQNRLRRQ REQEAADRPP
KSRLRKKRRE QDPTRTVDVG AGSAADSVLP HQQEPEAEQG AAAQAERDGG DREPEGKAAR
GLEGRDPRDV GRQKPECEAY EPNALYCICR QPHNNSLRFM ICCDRCEEWF HGDCVGISEA
RGRLLERNGE DYICPNCTIL QVQDETNSES AEQQEAKCTP ADGDGTDCTS MGTVEQKSGE
DQGIKGRIEK AANPSGKKKL KIFQPVAEAP GAAKCIGPGC SSAAQPDSVY CSSDCILKHA
AATMKFLSSG KEQKPKPKEK TKTKPEKLIL PKCSVQAGIR VSAVHKRPAP DKKENTVKKA
LVAPSRSEVL VKEAASEGTP SWASDHNYNA VKPEQTAALW PPLLYKSAKE DRRAEERTVA
PKRVAPAGPS AGGRQPAPRN LLPKKSPPFA NTAAAKVAIK KSPSGFKGPG PKRPWLSTTP
SSGAPPAKQA ALAPGAAASK KLPSSATLVG AVRKPGTASV PLASQAPGRL GTSNPALSQP
NSQIRQNIRR SLKEILWKRV NDSDDLIMTE SEVGKIALHI EKEMFNLFQV TDNRYKSRYR
SIMFNLKDPK NQGLFHRVLR EEISSAKLVR MKPEELASKE LSTWRERPAK PVLESRNKLP
SESKKTAAKQ ESVPDMEDSP PVSDSDEQQE SVRAVPDQSA APLLDVFSSM LKDTTGQHRA
HLFDLNCKIC TGQVPSSEDE PAPKKQKLSA SKKEEPKPQY EPPPSEPVLG SANEAMPETL
PESASEPDLD GAAHAHLERK YFPVPPGDSR PEPSALEGPS CPATCGGSVL TTVTVSGRDP
RTASSGSCTV TAPAAARPDG AHPAEPRQDV LKPAVTSVTV PKSILAKPSP SPEPRYLLPV
PPAPRVSLSE SRSPPEGDTT LFLSRLSTIW KGFINMQSVA KFVTKAYPVS GCCDYLSEDL
PDTIHIGGRI TPRTVWDYVG KLKSSVSKEL CLIRFHPATE EEEVAYISLY SYFSSRGRFG
VVANNSRHVK DLYLIPLSAK DPVPSKLLPF EGPGLESPRP NIILGLVICQ RIKRPSGAGE
LDKVEEKRTR PQTQEETEVS VYPKVSVAPQ SERKPPRFQV GSGDMAVSTT PPGTPPPPPP
PPEPPAASAS SSVLKILSSL KPGAPSTVPT APAAAALPTA APSANSSTSK TASPLEHILQ
TLFGKKKSFD PPAREPAESA PASHPDPKAK ADGGLPAAPL LDPIVQQFGQ LSKDRALEDE
EDDRPYDPEE EYGPERAFGA QLERGRRPDA EKAPETAERE EVAYDPEDET ILEEATVAID
DLPNRMCADG KGGAADRPAE PAAPGAAPSL VEQQQMIEEL NKQIEEQKRQ VAEQEAALRQ
QRAAVGASMA HFSVADALMS PPPKASLPQA ELFLQEQQTT GRPAALPGAP PAAGPGCDPR
PSRDPRQARR LAAEHCESEA GSRPPAARED GAEAALPAKP DGPKHEPSAS PVVLPAEGGP
PSAGSGSGSG SAPRPARRVL LPTPPSSAFQ PGFPLQSAQS FPSPGARDPF SAPVCTAQEK
CEDPRNAQFA EKGDPPAVEA EGDGEPPCRP GEGAATFPSA GQRAGAPLPP SQGQREPAPR
TFGTSGLHGP SFPGPRGPAP PFSEENIVSN SDGPRGPPPA RFGAQKGPIP SLFSGPHGPP
PYGDSRGPSP SHLGGPRGSA PPQFEERKDP HGEKREFQDG PYDEPAGPVP QFEGAEQSQF
VGGRGAAPFQ FGGQRRPLLS QFKGPRGGPP PPQFGGQRGP PPGHFVGPRG PHPNQFEGPR
GQAPNFMPGP RGVQPQPFEE QRVSSPPRFA NPRAPAPLPF GGPRGSVPFP EKSEPTPPRF
HFQGPPAPGL KAAPRPLLEL PSHPPPHRPE RWDEAPVQGP EPEFREAKGH DYRSAAFEGR
SRERFEAGPK EKPLDEPEAA PESRPGRALD ERRRERGRRW SRERDWERGH ERARHRDKDA
GREWDRSRER GADRDRGRDP ERASEWGRSR ERSRNRERER RRERERSRSR ERGRDRTREH
GRERKDRSKS KEGSRDPKAD APRAATPAGQ N
//
