ID M3YC51_MUSPF Unreviewed; 296 AA.
AC M3YC51;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=palmitoyl-protein hydrolase {ECO:0000256|ARBA:ARBA00012423};
DE EC=3.1.2.22 {ECO:0000256|ARBA:ARBA00012423};
GN Name=ABHD17B {ECO:0000313|Ensembl:ENSMPUP00000008908.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000008908.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000008908.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + S-hexadecanoyl-L-cysteinyl-[protein] = H(+) +
CC hexadecanoate + L-cysteinyl-[protein]; Xref=Rhea:RHEA:19233,
CC Rhea:RHEA-COMP:10131, Rhea:RHEA-COMP:11032, ChEBI:CHEBI:7896,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29950,
CC ChEBI:CHEBI:74151; EC=3.1.2.22;
CC Evidence={ECO:0000256|ARBA:ARBA00000072};
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. ABHD17 family.
CC {ECO:0000256|ARBA:ARBA00038397}.
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DR EMBL; AEYP01072463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01072464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01072465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YC51; -.
DR STRING; 9669.ENSMPUP00000008908; -.
DR Ensembl; ENSMPUT00000009055.1; ENSMPUP00000008908.1; ENSMPUG00000008981.1.
DR eggNOG; KOG1552; Eukaryota.
DR GeneTree; ENSGT00940000157611; -.
DR HOGENOM; CLU_029375_5_4_1; -.
DR InParanoid; M3YC51; -.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0014069; C:postsynaptic density; IEA:Ensembl.
DR GO; GO:0055038; C:recycling endosome membrane; IEA:Ensembl.
DR GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IEA:Ensembl.
DR GO; GO:1902817; P:negative regulation of protein localization to microtubule; IEA:Ensembl.
DR GO; GO:1905668; P:positive regulation of protein localization to endosome; IEA:Ensembl.
DR GO; GO:1902950; P:regulation of dendritic spine maintenance; IEA:Ensembl.
DR GO; GO:1902473; P:regulation of protein localization to synapse; IEA:Ensembl.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR InterPro; IPR029058; AB_hydrolase.
DR PANTHER; PTHR12277; ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12277:SF48; ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN 17B; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
SQ SEQUENCE 296 AA; 33622 MW; 3924B99A45CF47E2 CRC64;
MNNLSFSELC CLFCCPPCPG KIASKLAFLP PDPTYTLMCD ESGSRWTLHL SERADWQYSS
REKDAIECFM TRTSKGNRIA CMFVRCSPNA KYTLLFSHGN AVDLGQMSSF YIGLGSRINC
NIFSYDYSGY GASSGKPTEK NLYADIEAAW LALRTSYSTC QENMIIHIFN GRFIELQLIL
KYNCSFLKLN SSEELQSGLI MVYWKVCVSY CFFLIEDIDK ISKITSPVLI IHGTEDEVID
FSHGLALFER CQKPVEPLWV EGAGHNDVEL YGQYLERLKQ FVSQELSIAR AMASRR
//
