ID M3YCY8_MUSPF Unreviewed; 605 AA.
AC M3YCY8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Solute carrier family 23 member 1 {ECO:0000313|Ensembl:ENSMPUP00000009195.1};
GN Name=SLC23A1 {ECO:0000313|Ensembl:ENSMPUP00000009195.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000009195.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000009195.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; AEYP01016679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YCY8; -.
DR STRING; 9669.ENSMPUP00000009195; -.
DR Ensembl; ENSMPUT00000009348.1; ENSMPUP00000009195.1; ENSMPUG00000009270.1.
DR eggNOG; KOG1292; Eukaryota.
DR GeneTree; ENSGT00950000182953; -.
DR HOGENOM; CLU_017959_5_4_1; -.
DR InParanoid; M3YCY8; -.
DR OMA; AHANSEM; -.
DR GO; GO:0016324; C:apical plasma membrane; IEA:Ensembl.
DR GO; GO:0009925; C:basal plasma membrane; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0043229; C:intracellular organelle; IEA:Ensembl.
DR GO; GO:0033300; F:dehydroascorbic acid transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0008520; F:L-ascorbate:sodium symporter activity; IEA:Ensembl.
DR GO; GO:0015229; F:L-ascorbic acid transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0015143; F:urate transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0007420; P:brain development; IEA:Ensembl.
DR GO; GO:0030324; P:lung development; IEA:Ensembl.
DR GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR11119:SF21; SOLUTE CARRIER FAMILY 23 MEMBER 1; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 580..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 65593 MW; CEC8F100512A4DBB CRC64;
MRAQENLEGR TQHESLGSAG NSERDPMESL PREPKFDMLY KIEDVPPWYL CILLGFQHYL
TCFSGTIAVP FLLAEALCVG RDQHMVSQLI GTIFTCVGIT TLIQTTLGIR LPLFQASAFA
FLVPAKAILA LERWKCPPEE DIYGNWSLPL NTSHIWHPRI REVQGAIIVS SMVEVVIGLM
GLPGALLSYI GPLTVTPTVS LIGLSVFQAA GDRAGSHWGI SACSILLIIL FSQYLRNLTF
LLPIYRWGKG LTLFRIQIFK MFPIVLAIMT VWLLCYILTL TNVLPSDPTA YGFQARTDAR
GDIMAIAPWI RIPYPCQWGL PTVTAAAVLG MFSATLAGII ESIGDYYACA RLAGAPPPPV
HAINRGIFTE GICCIIAGLL GTGNGSTSSS PNIGVLGITK VGSRRVVQYG AGIMLVLGTV
GKFTALFASL PDPILGGMFC TLFGMITAVG LSNLQFVDMN SSRNLFVLGF SMFFGLTLPN
YLESNPGTIN TGIPEVDQIL TVLLTTEMFV GGCLAFILDN TVPGSPEERG LIQWKAGAHA
NSEMSTSLKS YDFPIGMNIV KRIAFLKYIP ICPVFKGFSS RSKTQPPVPE DTPENIQTGS
ACTKV
//
