ID M3YE21_MUSPF Unreviewed; 372 AA.
AC M3YE21;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Reticulon 4 interacting protein 1 {ECO:0000313|Ensembl:ENSMPUP00000009578.1};
GN Name=RTN4IP1 {ECO:0000313|Ensembl:ENSMPUP00000009578.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000009578.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000009578.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. Quinone oxidoreductase subfamily.
CC {ECO:0000256|ARBA:ARBA00010371}.
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DR EMBL; AEYP01034055; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YE21; -.
DR STRING; 9669.ENSMPUP00000009578; -.
DR Ensembl; ENSMPUT00000009734.1; ENSMPUP00000009578.1; ENSMPUG00000009654.1.
DR eggNOG; KOG1198; Eukaryota.
DR GeneTree; ENSGT00880000138028; -.
DR HOGENOM; CLU_026673_3_3_1; -.
DR InParanoid; M3YE21; -.
DR OMA; MKAWAYD; -.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:Ensembl.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08248; RTN4I1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR InterPro; IPR037397; RTN4I1.
DR PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 3: Inferred from homology;
FT DOMAIN 52..329
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT REGION 329..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 40758 MW; B140254C408A025D CRC64;
MEFLKTCVLR RNACNAVCFW RSRAVQKLSV RKISTTSPRS TVMPAWVIDK YGKNEVLRFT
QNMMIPVIHY PNEVIIKVHA ASVNPIDVNM RSGYGATALN IKRDPLHIKT KGEEFPLTLG
RDVSGVVMEC GLDVRYFKPG DEVWAAVPPW KQGTLSEFVV VSGNEVSLKP KSLTHTQAAS
LPYVALTAWS AINKVGGLND KNCTGKRVLI LGASGGVGTF AIQVMKAWGA HVTAVCSQDA
SELVRKLGAD DVVDYKSGSV EEQLKSLKPF DFILDNVGGS TETWALNFLK KWSGATYVTL
VTPFLLNMDR LGIADGMLQT GVTVGSKALK RSQVGRERGR EAGSPLSREP DAELDPRTLR
SRPERKAEAL TH
//
