ID M3YJP8_MUSPF Unreviewed; 615 AA.
AC M3YJP8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=SRY-box transcription factor 13 {ECO:0000313|Ensembl:ENSMPUP00000011555.1};
GN Name=SOX13 {ECO:0000313|Ensembl:ENSMPUP00000011555.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000011555.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000011555.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
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DR EMBL; AEYP01041231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01041232; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004756438.1; XM_004756381.2.
DR RefSeq; XP_004756439.1; XM_004756382.2.
DR RefSeq; XP_004756441.1; XM_004756384.2.
DR AlphaFoldDB; M3YJP8; -.
DR STRING; 9669.ENSMPUP00000011555; -.
DR Ensembl; ENSMPUT00000011746.1; ENSMPUP00000011555.1; ENSMPUG00000011648.1.
DR eggNOG; KOG0528; Eukaryota.
DR GeneTree; ENSGT00940000158759; -.
DR HOGENOM; CLU_018522_1_1_1; -.
DR InParanoid; M3YJP8; -.
DR OMA; MEETPGH; -.
DR OrthoDB; 2902801at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0042492; P:gamma-delta T cell differentiation; IEA:Ensembl.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR GO; GO:0090336; P:positive regulation of brown fat cell differentiation; IEA:Ensembl.
DR GO; GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Ensembl.
DR GO; GO:0021529; P:spinal cord oligodendrocyte cell differentiation; IEA:Ensembl.
DR CDD; cd22030; HMG-box_SoxD; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR45789; FI18025P1; 1.
DR PANTHER; PTHR45789:SF4; TRANSCRIPTION FACTOR SOX-13; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267}.
FT DOMAIN 417..485
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 417..485
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 26..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 575..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 174..211
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 62..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..593
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 68223 MW; 644925A9336BB3F8 CRC64;
MSMRSPGSAQ LAPDGVGTMV NCTVKSEGKK EPCHEALQGS AAAAEPQPGD PARAPQDAVD
SQAPAQDCSS PESNGSPEPK RLGASEAPSG SQEKLDFNQH LKEVVPAIEK LLSSDWKERF
LGRSSVETKD VKGTQESLAE KELQLLVMIH QLSTLRDQLL TAHSEQKNMA AMLFEKQQQQ
MELARQQQEQ IAKQQQQLIQ QQHKINLLQQ QIQQVNMPYV MIPAFPPSHQ PLPVTPESQL
ALPIQPIPCK PVDYPLPLLH TPPAPVVKRP GAMAAHHPLQ EPSQPLNLTA KPKAPELPSA
SSSPSLKMNN CGPRPPSHGA PTRDLQASPP SLPLGFLGEG DAVTKAIQDA RQLLHGHSGA
LESSPNAPFR KDLISLDTSP AKERLEESCV HPLEEAMLGC DMDGSRHFPE SRNSSHIKRP
MNAFMVWAKD ERRKILQAFP DMHNSSISKI LGSRWKSMTN QEKQPYYEEQ ARLSRQHLEK
YPDYKYKPRP KRTCIVEGKR LRVGEYKALM RTRRQDARQS YVTPPQAGQL QMSSPDVLYP
RVAGVPLAQP LVEHYVPRSL DPNMPVIVNT CSLREEGEAT EDRHSVAEGE LYRYSEDEDS
EGEEKSDGEL VVLTD
//
