ID M3YKN8_MUSPF Unreviewed; 405 AA.
AC M3YKN8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Double PHD fingers 2 {ECO:0000313|Ensembl:ENSMPUP00000011895.1};
DE SubName: Full=Zinc finger protein ubi-d4 isoform X1 {ECO:0000313|RefSeq:XP_004770123.1};
GN Name=DPF2 {ECO:0000313|Ensembl:ENSMPUP00000011895.1,
GN ECO:0000313|RefSeq:XP_004770123.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000011895.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000011895.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004770123.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004770123.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AEYP01074211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004770123.1; XM_004770066.3.
DR STRING; 9669.ENSMPUP00000011895; -.
DR Ensembl; ENSMPUT00000012090.1; ENSMPUP00000011895.1; ENSMPUG00000011987.1.
DR GeneID; 101686153; -.
DR KEGG; mpuf:101686153; -.
DR CTD; 5977; -.
DR eggNOG; KOG1244; Eukaryota.
DR GeneTree; ENSGT00940000155070; -.
DR HOGENOM; CLU_038980_0_1_1; -.
DR OMA; EHSKDAW; -.
DR OrthoDB; 5490909at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0062072; F:H3K9me3 modified histone binding; IEA:Ensembl.
DR GO; GO:0070577; F:lysine-acetylated histone binding; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:1905454; P:negative regulation of myeloid progenitor cell differentiation; IEA:Ensembl.
DR CDD; cd15691; PHD1_DPF2_like; 1.
DR CDD; cd15530; PHD2_d4; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR025750; DPF1-3_N.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR PANTHER; PTHR45888:SF13; ZINC FINGER PROTEIN UBI-D4; 1.
DR Pfam; PF14051; DPF1-3_N; 1.
DR Pfam; PF00628; PHD; 2.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 284..344
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 341..391
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 79..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 166..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 45794 MW; 5FFC5A781BDA98C9 CRC64;
MAAVVENVVK LLGEQYYKDA MEQCHNYNAR LCAERSVRLP FLDSQTGVAQ SNCYIWMEKR
HRGPGLASGQ LYSYPARRWR KKRRAHPPED PRLSFPSIKP DTDQTLKKEG LISQDGSSLE
ALLRTDPLEK RGAPDPRVDD DSLGEFPVTN SRARKRILEP EDFLDDLDDE DYEEDTPKRR
GKGKSKGKGV GSARKKLDAS ILEDRDKPYA CDNSFKQKHT SKAPQRVCGK RYKNRPGLSY
HYAHSHLAEE EGEDKEDSQP PTPVSQRSEE QKSKKGPDGL ALPNNYCDFC LGDSKINKKT
GQPEELVSCS DCGRSGHPSC LQFTPVMMAA VKTYRWQCIE CKCCNICGTS ENDDQLLFCD
DCDRGYHMYC LTPSMSEPPE GSWSCHLCLD LLKEKASIYQ NQNSS
//
