ID M3YKU6_MUSPF Unreviewed; 858 AA.
AC M3YKU6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Tetratricopeptide repeat domain 7A {ECO:0000313|Ensembl:ENSMPUP00000011953.1};
DE SubName: Full=Tetratricopeptide repeat protein 7A isoform X2 {ECO:0000313|RefSeq:XP_004753064.1};
GN Name=TTC7A {ECO:0000313|Ensembl:ENSMPUP00000011953.1,
GN ECO:0000313|RefSeq:XP_004753064.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000011953.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000011953.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004753064.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004753064.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AEYP01033039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01033040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004753064.1; XM_004753007.2.
DR STRING; 9669.ENSMPUP00000011953; -.
DR Ensembl; ENSMPUT00000012148.1; ENSMPUP00000011953.1; ENSMPUG00000012045.1.
DR GeneID; 101682371; -.
DR KEGG; mpuf:101682371; -.
DR CTD; 57217; -.
DR eggNOG; KOG4162; Eukaryota.
DR GeneTree; ENSGT00940000158638; -.
DR HOGENOM; CLU_010512_1_0_1; -.
DR OMA; CRSECNW; -.
DR OrthoDB; 25200at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR GO; GO:0006879; P:intracellular iron ion homeostasis; IEA:Ensembl.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR045819; TTC7_N.
DR PANTHER; PTHR23083:SF475; TETRATRICOPEPTIDE REPEAT PROTEIN 7A; 1.
DR PANTHER; PTHR23083; TETRATRICOPEPTIDE REPEAT PROTEIN, TPR; 1.
DR Pfam; PF07719; TPR_2; 1.
DR Pfam; PF13181; TPR_8; 1.
DR Pfam; PF19440; TTC7_N; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 8..403
FT /note="Tetratricopeptide repeat protein 7 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19440"
FT REPEAT 745..778
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 813..846
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 858 AA; 96088 MW; E034EA3CDF555CAC CRC64;
MAAKGAHGSH LKVESELERC RAEGHWDRMP ELVRQLQTLV VPGGGGNRRT SPSAAFTSLD
TDDLGKLLLA EALLEQCLKE NHTKIKDSIP LPEKNEPKMN EARNHLSSIL NHGRLSPQYL
CEAMLIQGKL HYMEGSYRDA ISMYARAGID DMSMENKPLY QMRLLAEAFV IKGLSLERLP
NSIASRHRLT EREEEVITCF ERASWIAQVF LQELEKITSN TTSRHLKGSH PVDYELTYFL
EAALQSAYVT NLKKGNIVKG MRELREVLRT VETKATQNFK VMAAKHLAGV LLHSLSEECY
WSPLSHPLPE FMSKEENSFI TQALRKPHLY EGDNLYCPKD NIEEALLLLL ISESMATRDV
VLSRAPEQEE DRAASLRNAA AIYDLLSITL GRRGQYVMLS ECLERAMKFA FEEFHLWYQV
ALSMVACGKS AYAVSLLQEC MKLRPSDPTV PLMAAKVCIG SLHWLEDAER FAMMVINLGE
EAGEFLAKGY LALGLTYSLQ ATDATLKSKQ DELHRKALQT LDRAQQLAPG DPQVILYVSL
QLALVRQISS AMEQLQEALK VCGDDANALH LLALLFSAQK YYQHALDVIN MAITEYPENF
NLMFTKVKLE QVLKGPEEAL VTCRQMLRLW QTLYNFSQMG GLEKDGSLGE GITLKKQSGM
HLTLPDAHDA DSGSRHASSI AASRLEEAMS ELTVPSSVLK QGPMQLWTTL EQIWLQAAEL
FMEQRHLKEA GFCIQEAAGL FPTSHSVLYM RGRLAEMKGN LEEAEQLYKE ALTVNPDGVR
IMHSLGLMLS RLGHKSLAQK VLRDAVERQS TCHEAWQGLG EVLQAQGQSE AAVDCFLTAL
ELEASSPVLP FSIIPREL
//
