ID M3YPD4_MUSPF Unreviewed; 417 AA.
AC M3YPD4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Speckle type BTB/POZ protein like {ECO:0000313|Ensembl:ENSMPUP00000013192.1};
DE SubName: Full=Speckle-type POZ protein-like isoform X1 {ECO:0000313|RefSeq:XP_012904356.1, ECO:0000313|RefSeq:XP_012904357.1};
GN Name=SPOPL {ECO:0000313|Ensembl:ENSMPUP00000013192.1,
GN ECO:0000313|RefSeq:XP_012904356.1, ECO:0000313|RefSeq:XP_012904357.1,
GN ECO:0000313|RefSeq:XP_012904358.1, ECO:0000313|RefSeq:XP_044922377.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000013192.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000013192.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_012904356.1, ECO:0000313|RefSeq:XP_012904357.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_012904356.1,
RC ECO:0000313|RefSeq:XP_012904357.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Tdpoz family.
CC {ECO:0000256|ARBA:ARBA00010846}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEYP01094226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01094227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012904356.1; XM_013048902.2.
DR RefSeq; XP_012904357.1; XM_013048903.2.
DR RefSeq; XP_012904358.1; XM_013048904.2.
DR RefSeq; XP_044922377.1; XM_045066442.1.
DR STRING; 9669.ENSMPUP00000013192; -.
DR Ensembl; ENSMPUT00000013403.1; ENSMPUP00000013192.1; ENSMPUG00000013290.1.
DR GeneID; 101685797; -.
DR CTD; 339745; -.
DR eggNOG; KOG1987; Eukaryota.
DR GeneTree; ENSGT00940000155953; -.
DR HOGENOM; CLU_004253_2_0_1; -.
DR OMA; LCTFTVM; -.
DR OrthoDB; 5473088at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031397; P:negative regulation of protein ubiquitination; IEA:Ensembl.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR CDD; cd18519; BACK_SPOPL; 1.
DR CDD; cd18343; BTB_POZ_SPOPL; 1.
DR Gene3D; 6.20.250.50; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR008974; TRAF-like.
DR PANTHER; PTHR24413; SPECKLE-TYPE POZ PROTEIN; 1.
DR PANTHER; PTHR24413:SF91; SPECKLE-TYPE POZ PROTEIN-LIKE; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00917; MATH; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50144; MATH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000715}.
FT DOMAIN 31..161
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT DOMAIN 200..262
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 417 AA; 47470 MW; 60F781C5B9F56374 CRC64;
MSREPSPPLP GDMSTGPIAE SWCYTQVKVV KFSYMWTINN FSFCREEMGE VLKSSTFSSS
PSDKMKWCLR VNPKGLDDES KDYLSLYLLL VSCPKSEVRA KFKFSLLNAK REETKAMESQ
RAYRFVQGKD WGFKKFIRRD FLLDEANGLL PDDKLTLFCE VSVVQDSVNI SGHTNTNTLK
VPECRLAEDL GNLWENTRFT DCSFFVRGQE FKAHKSVLAA RSPVFNAMFE HEMEESKKNR
VEINDVDPEV FKEMMRFIYT GKAPNLDKMA DNLLAAADKY ALERLKVMCE EALCSNLSVE
NVADTLVLAD LHSAEQLKAQ AIDFINRCSV LRQLGCKDGK NWNSKMICLC FIIFQNQRSV
DGVKNLSCFC QAADIMETSG WKSMIQSHPH LVAEAFRALA SAQCPQFGIP RKRLKQS
//
