ID M3YPV8_MUSPF Unreviewed; 499 AA.
AC M3YPV8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Solute carrier family 25 member 25 {ECO:0000313|Ensembl:ENSMPUP00000013366.1};
GN Name=SLC25A25 {ECO:0000313|Ensembl:ENSMPUP00000013366.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000013366.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000013366.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; AEYP01042626; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042627; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01042628; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3YPV8; -.
DR STRING; 9669.ENSMPUP00000013366; -.
DR Ensembl; ENSMPUT00000013581.1; ENSMPUP00000013366.1; ENSMPUG00000013468.1.
DR eggNOG; KOG0036; Eukaryota.
DR GeneTree; ENSGT00940000157207; -.
DR HOGENOM; CLU_015166_2_0_1; -.
DR InParanoid; M3YPV8; -.
DR OMA; YLHEHEM; -.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140987; F:ATP:inorganic phosphate antiporter activity; IEA:Ensembl.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR GO; GO:0046034; P:ATP metabolic process; IEA:Ensembl.
DR GO; GO:0070588; P:calcium ion transmembrane transport; IEA:Ensembl.
DR GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR GO; GO:0045333; P:cellular respiration; IEA:Ensembl.
DR GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR GO; GO:0002021; P:response to dietary excess; IEA:Ensembl.
DR GO; GO:0032094; P:response to food; IEA:Ensembl.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR24089:SF769; CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN SCAMC-2; 1.
DR PANTHER; PTHR24089; SOLUTE CARRIER FAMILY 25; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SMART; SM00054; EFh; 4.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50222; EF_HAND_2; 3.
DR PROSITE; PS50920; SOLCAR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT DOMAIN 50..85
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 86..121
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 154..189
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 308..393
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 405..493
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 499 AA; 55009 MW; 30A462956481424A CRC64;
RSAPGAPASR PMVSSVLCRC VASPPPDAAS AASSPASVDP CGGAVCGGPD HRLRLWSLFQ
TLDVNRDGGL CVNDLAVGLR RLGLHRTEGE LRKIVQAGDK DLDGQLDFEE FVHYLQDHEK
KLRLVFKSLD KKNDAGRIDA QEIMQSLRDL GVKISEQQAE KILKSMDKNG TMTIDWNEWR
DYHLLHPVEN IPEIILYWKH STIFDVGENL TVPDEFTVEE RQTGMWWRHL VAGGGAGAVS
RTCTAPLDRL KVLMQNYCSD EGNRRSGSKY SFARGTFHCI WGRKARGHIT GLKCGQIKRL
VGSDQEALRI HERLVAGSLA GAIAQSSIYP MEVLKTRMAL RKTGQYSGML DCARKILARE
GVAAFYKGYV PNMLGIIPYA GIDLAVYETL KNAWLQRYAV NSADPGVFVL LACGTMSSTC
GQLASYPLAL VRTRMQAQAS IEGAPEVTMS SLFRQILRTE GAFGLYRGLA PNFMKVIPAV
SISYVVYENL KITLGVQSR
//
