ID M3YW31_MUSPF Unreviewed; 679 AA.
AC M3YW31;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=WD and tetratricopeptide repeats 1 {ECO:0000313|Ensembl:ENSMPUP00000015541.1};
DE SubName: Full=WD and tetratricopeptide repeats protein 1 isoform X1 {ECO:0000313|RefSeq:XP_004741132.1};
GN Name=WDTC1 {ECO:0000313|Ensembl:ENSMPUP00000015541.1,
GN ECO:0000313|RefSeq:XP_004741132.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000015541.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000015541.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004741132.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004741132.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEYP01008109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01008110; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01008111; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01008112; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01008113; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004741132.1; XM_004741075.3.
DR STRING; 9669.ENSMPUP00000015541; -.
DR Ensembl; ENSMPUT00000015782.1; ENSMPUP00000015541.1; ENSMPUG00000015651.1.
DR GeneID; 101670671; -.
DR KEGG; mpuf:101670671; -.
DR CTD; 23038; -.
DR eggNOG; KOG1310; Eukaryota.
DR eggNOG; KOG1334; Eukaryota.
DR GeneTree; ENSGT00950000182900; -.
DR HOGENOM; CLU_012381_3_1_1; -.
DR OMA; YKQRYVG; -.
DR OrthoDB; 66220at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0004857; F:enzyme inhibitor activity; IEA:Ensembl.
DR GO; GO:0042393; F:histone binding; IEA:Ensembl.
DR GO; GO:0042826; F:histone deacetylase binding; IEA:Ensembl.
DR GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR GO; GO:0055082; P:intracellular chemical homeostasis; IEA:Ensembl.
DR GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IEA:Ensembl.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045151; DCAF8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15574:SF40; WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1; 1.
DR PANTHER; PTHR15574; WD REPEAT DOMAIN-CONTAINING FAMILY; 1.
DR Pfam; PF00400; WD40; 4.
DR SMART; SM00028; TPR; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 43..75
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 86..129
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 548..577
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 578..610
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 488..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 679 AA; 75975 MW; 124F459C32DBCF2C CRC64;
MAKVNITRDL IRRQIKERGA LSFERHYHVT DPFIRRLGLE AELQGHSGCV NCLEWNEKGD
LLASGSDDQH TIVWDPLHHK KLLSMHTGHT ANIFSVKFLP HAGDRILITG AADSKVHVHD
LTVKETIHMF GDHTNRVKRI ATAPMWPNTF WSAAEDGLIR QYDLRENSKH SEVLIDLTEY
CGQLVEAKCL TVNPQDNNCL AVGASGPFVR LYDIRMIHNH RKSMKQSPSA GVHTFCDRQK
PLPDGAAQYY VAGHLPVKLP DYNNRLRVLV ATYVTFSPNG TELLVNMGGE QVYLFDLTYK
QRPYTFLLPR KCHSSGEVQN GKMSTNGVSN GVSNGLHLHS NGFRLPESRG HVSPQVELPP
YLERVKQQAN EAFACQQWTQ AIQLYSKAVQ RAPHNAMLYG NRAAAYMKRK WDGDHYDALR
DCLKAISLNP CHLKAHFRLA RCLFELKYVA EALECLDDFK GKFPEQAHSS ACDALGRDIT
AALFSKNDGE EKKGAGGGGG GPVRLRSTSR KDSISEDEMV LRERSYDYQF RYCGHCNTTT
DIKEANFFGS NAQYIVSGSD DGSFFIWEKE TTNLVRVLQG DESIVNCLQP HPSYCFLATS
GIDPVVRLWN PRPESEDLTG RVVEDMEGAS QANQRRMNAD PLEVMLLNMG YRITGLSSGG
AGASDDEDSS EGQVQCRPS
//
