ID   M3Z002_MUSPF            Unreviewed;       437 AA.
AC   M3Z002;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=Tr-type G domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000016913.1};
RN   [1] {ECO:0000313|Ensembl:ENSMPUP00000016913.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR   EMBL; AEYP01002809; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M3Z002; -.
DR   STRING; 9669.ENSMPUP00000016913; -.
DR   Ensembl; ENSMPUT00000017164.1; ENSMPUP00000016913.1; ENSMPUG00000017019.1.
DR   eggNOG; KOG0052; Eukaryota.
DR   GeneTree; ENSGT00940000154037; -.
DR   HOGENOM; CLU_007265_3_5_1; -.
DR   InParanoid; M3Z002; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   CDD; cd03693; EF1_alpha_II; 1.
DR   CDD; cd03705; EF1_alpha_III; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 2.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   PANTHER; PTHR23115:SF222; ELONGATION FACTOR 1-ALPHA 1-RELATED; 1.
DR   PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          8..187
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|Pfam:PF00009"
FT   DOMAIN          245..308
FT                   /note="Translation elongation factor EFTu-like"
FT                   /evidence="ECO:0000259|Pfam:PF03144"
FT   DOMAIN          319..417
FT                   /note="Translation elongation factor EFTu/EF1A C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03143"
SQ   SEQUENCE   437 AA;  47656 MW;  977EC5762015984D CRC64;
     MGKENIQINI VVIGHVVDSG KSTTTGHLIY KCGGIDKRTM EKFEKEAADM EKGSFKYAIL
     DQLKAAHECG ITVDISLWKF ETSKYYAPGH RDFKNMIMDT SQPDCTVLIV ATGVGEFEAG
     ISKNGQAHEH ALLAYTLVKT DSMEPHYNQK SYREVIKADN TYIKKIGYNP NRVAFVPISG
     WNGDNMLEPS AKVPWFKGWK VIPKMGIPVE PQCLSFGLHS ATTHSTDKRL HLPLQDVFKF
     GGVDTVPVGR MAAGVLKPGI VTFAPVNVTT EVKSVEMHHE TLSEALPGDI VGFHVKNVPV
     KEVHCGNVAG DSKNDPLRDA AGFTAQVIIL NHPGQISAGY VPVLDYHTAH IACRFAELKE
     KKLEDGPKFL KSGDAAIVDM VPGKPMCVES CSDYPLWGHF AVCETRQTVA VGVIKAVDRK
     AAGGNTAKTA QKAQKAK
//