ID M3Z5W9_MUSPF Unreviewed; 525 AA.
AC M3Z5W9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Tigger transposable element derived 2 {ECO:0000313|Ensembl:ENSMPUP00000018981.1};
DE SubName: Full=Tigger transposable element-derived protein 2 {ECO:0000313|RefSeq:XP_004756141.1};
GN Name=TIGD2 {ECO:0000313|Ensembl:ENSMPUP00000018981.1,
GN ECO:0000313|RefSeq:XP_004756141.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000018981.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000018981.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004756141.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004756141.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
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DR EMBL; AEYP01040739; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004756141.1; XM_004756084.3.
DR STRING; 9669.ENSMPUP00000018981; -.
DR Ensembl; ENSMPUT00000019256.1; ENSMPUP00000018981.1; ENSMPUG00000019104.1.
DR GeneID; 101692347; -.
DR KEGG; mpuf:101692347; -.
DR CTD; 166815; -.
DR eggNOG; KOG3105; Eukaryota.
DR GeneTree; ENSGT00940000162273; -.
DR HOGENOM; CLU_018294_1_1_1; -.
DR OMA; QWFDSQS; -.
DR OrthoDB; 2967227at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR PANTHER; PTHR19303:SF22; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 2; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715}.
FT DOMAIN 1..52
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 67..139
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 28..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
FT REGION 445..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..473
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 59731 MW; 39EA2FF74749D1D7 CRC64;
MLGKRKRVVL TIKDKLDIIK KLEEGISFKK LSVVYGIGES TVRDIKKNKE RIINYANSSD
PTSGVSKRKS MKSSTYEELD RVMIEWFNQQ KTDGIPVSGT ICAKQAKFFF DALGMEGDFN
ASSGWLTRFK QRHGIPKAAG KGTKLKGDET AASEFCGNFQ EFVERENLQP EQIYGADQTG
LFWKCLPSRT LALETEQNTS GYRSSRERII IMCCANATGL HKLNLCVVGK AKKPRAFKGA
DLSNLPVTYF SQKSAWIEHS VFRQWFEKYF VPQVQKHLKS QGLLEKAVLL LDFPPAHPNE
ELLSSDDGRI IVKYLPPNVT SLIQPMSQGV LATVKRYYRA GLLQKYMGEG IDPKMFWKNL
TVLDAIYEVS RAWNMVKSST ITKAWKKLFP SNEENSGMNI DEGAILAANL ATVLQNTEAC
EHVDIENIDQ WFDSRSNDSS CQVLTDSESA EDQAKPAEQK HYNKTRKADL NPEKHISHKA
ALEWTENLLD YLEQQDDMLL SDKLVLRRLR TIIRRKQKIQ NNKNH
//
