ID M3Z868_MUSPF Unreviewed; 439 AA.
AC M3Z868;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE SubName: Full=Potassium voltage-gated channel subfamily A member 3 {ECO:0000313|Ensembl:ENSMPUP00000019781.1};
GN Name=KCNA3 {ECO:0000313|Ensembl:ENSMPUP00000019781.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000019781.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000019781.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AEYP01073800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3Z868; -.
DR STRING; 9669.ENSMPUP00000019781; -.
DR Ensembl; ENSMPUT00000020063.1; ENSMPUP00000019781.1; ENSMPUG00000019911.1.
DR eggNOG; KOG1545; Eukaryota.
DR GeneTree; ENSGT00940000160210; -.
DR HOGENOM; CLU_011722_4_0_1; -.
DR InParanoid; M3Z868; -.
DR OMA; INHSAFK; -.
DR GO; GO:0030424; C:axon; IEA:Ensembl.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF28; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01496; SHAKERCHANEL.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..60
FT /note="Potassium channel tetramerisation-type BTB"
FT /evidence="ECO:0000259|Pfam:PF02214"
FT DOMAIN 101..354
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 439 AA; 49510 MW; 7D3B01584ADA2463 CRC64;
MRYFDPLRNE YFFDRNRPSF DAILYYYQSG GRIRRPVNVP IDIFSEEIRF YQLGEEAMEK
FREDEGFLRE EERPLPRRDF QRQVWLLFEY PESSGPARGI AIVSVLVILI SIVIFCLETL
PEFRDEKDYP AASSQEQFEA ASNSTSGAPA GASSFSDPFF VVETLCIIWF SFELLVRFFA
CPSKATFSRN IMNLIDIVAI IPYFITLGTE LAERQGNGQQ AMSLAILRVI RLVRVFRIFK
LSRHSKGLQI LGQTLKASMR ELGLLIFFLF IGVILFSSAV YFAEADDPTS GFSSIPDAFW
WAVVTMTTVG YGDMHPVTIG GKIVGSLCAI AGVLTIALPV PVIVSNFNYF YHRETEGEEQ
AQYMHVGSCQ HLSSSAEELR KARSNSTLSK SEYMVIEEGG MNHSAFPQTP FKTGNSTATC
TTNNNPNSCV NIKKIFTDV
//
