UniProt: M3Z8N1

Database: UniProt
Entry: M3Z8N1_MUSPF

LinkDB:  M3Z8N1_MUSPF 
Original site:  M3Z8N1_MUSPF

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Ontology (3)   
   GO (3)   
Gene (5)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
   ENSEMBL-UP (3)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (6)   
   InterPro (3)   
   Pfam (1)   
   PROSITE (2)   
All databases (16)   

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ID   M3Z8N1_MUSPF            Unreviewed;       312 AA.
AC   M3Z8N1;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=OR8S1 {ECO:0000313|Ensembl:ENSMPUP00000019945.1};
GN   Synonyms=LOC101683170 {ECO:0000313|RefSeq:XP_004778994.1};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000019945.1};
RN   [1] {ECO:0000313|Ensembl:ENSMPUP00000019945.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2023) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_004778994.1}
RP   IDENTIFICATION.
RC   TISSUE=Brain {ECO:0000313|RefSeq:XP_004778994.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Putative odorant or sperm cell receptor.
CC       {ECO:0000256|ARBA:ARBA00003929}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363047};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688}.
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DR   EMBL; AEYP01095623; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_004778994.1; XM_004778937.1.
DR   STRING; 9669.ENSMPUP00000019945; -.
DR   Ensembl; ENSMPUT00000020229.1; ENSMPUP00000019945.1; ENSMPUG00000020077.1.
DR   GeneID; 101683170; -.
DR   KEGG; mpuf:101683170; -.
DR   eggNOG; ENOG502SI96; Eukaryota.
DR   GeneTree; ENSGT00940000159881; -.
DR   HOGENOM; CLU_012526_1_0_1; -.
DR   OMA; AFTCSAH; -.
DR   OrthoDB; 5401587at2759; -.
DR   Proteomes; UP000000715; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   CDD; cd15229; 7tmA_OR8S1-like; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   PANTHER; PTHR48001; OLFACTORY RECEPTOR; 1.
DR   PANTHER; PTHR48001:SF103; OLFACTORY RECEPTOR 8S1; 1.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU363047};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW   ECO:0000256|RuleBase:RU000688};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW   Olfaction {ECO:0000256|RuleBase:RU363047};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000313|RefSeq:XP_004778994.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000688};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM        25..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        60..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        98..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        140..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        196..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   DOMAIN          41..288
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
SQ   SEQUENCE   312 AA;  34671 MW;  D7345000540A1970 CRC64;
     MDLGNYSTIT EFILLGLSAN PHIQAALFVL FLGIYLLTIM GNLMLLLVIR ADFHLHTPMY
     FFLSHLSFVD ICFSSVTVPK MLENLLSQKK TISVEGCLTQ VFFVFVAAGT EACLLSVMAY
     DRYAAICHPL LYGQIMSKQL YMQLAWGSWG LGFLDAFINI FLAMKMVFCK AQIIPHFSCE
     MPSLLSLSCS DISRNLIALL CSTLLHGLGT FLLVFLSYAC IITTILSISS TTGRSKAFST
     CSSHLTAVTL YYGSGLLHNL MPNSGSPLEL IFSVQYTVVT PMLNPLIYSL KNKEVKAALT
     RTLEKYLQHI RC
//

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