ID M3ZBG8_NOMLE Unreviewed; 227 AA.
AC M3ZBG8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Ras-related protein Rab-3 {ECO:0000256|RuleBase:RU367096};
GN Name=RAB3C {ECO:0000313|Ensembl:ENSNLEP00000024055.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000024055.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000024055.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000024055.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Protein transport. Probably involved in vesicular traffic.
CC {ECO:0000256|RuleBase:RU367096}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU367096};
CC Lipid-anchor {ECO:0000256|RuleBase:RU367096}; Cytoplasmic side
CC {ECO:0000256|RuleBase:RU367096}. Membrane
CC {ECO:0000256|ARBA:ARBA00004423}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004423}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004423}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270, ECO:0000256|RuleBase:RU367096}.
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DR EMBL; ADFV01030832; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01030833; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01030834; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01030835; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01030836; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01030837; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01030838; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01030839; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01030840; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003266004.1; XM_003265956.3.
DR AlphaFoldDB; M3ZBG8; -.
DR SMR; M3ZBG8; -.
DR STRING; 61853.ENSNLEP00000024055; -.
DR Ensembl; ENSNLET00000032427.2; ENSNLEP00000024055.2; ENSNLEG00000002575.3.
DR GeneID; 100586719; -.
DR KEGG; nle:100586719; -.
DR CTD; 115827; -.
DR GeneTree; ENSGT00940000157368; -.
DR InParanoid; M3ZBG8; -.
DR OMA; PSSQCNC; -.
DR OrthoDB; 8685at2759; -.
DR Proteomes; UP000001073; Chromosome 18.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008021; C:synaptic vesicle; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030742; F:GTP-dependent protein binding; IEA:Ensembl.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0031489; F:myosin V binding; IEA:Ensembl.
DR GO; GO:0019882; P:antigen processing and presentation; IEA:Ensembl.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
DR CDD; cd01865; Rab3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR037872; Rab3.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47980; LD44762P; 1.
DR PANTHER; PTHR47980:SF15; RAS-RELATED PROTEIN RAB-3C; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU367096};
KW GTP-binding {ECO:0000256|RuleBase:RU367096};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288, ECO:0000256|RuleBase:RU367096};
KW Membrane {ECO:0000256|RuleBase:RU367096};
KW Methylation {ECO:0000256|ARBA:ARBA00022481, ECO:0000256|RuleBase:RU367096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU367096};
KW Prenylation {ECO:0000256|ARBA:ARBA00023289, ECO:0000256|RuleBase:RU367096};
KW Protein transport {ECO:0000256|RuleBase:RU367096};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transport {ECO:0000256|RuleBase:RU367096}.
SQ SEQUENCE 227 AA; 25952 MW; 7352E205DEFAC72D CRC64;
MRHEAPMQMA SAQDARYGQK DSSDQNFDYM FKLLIIGNSS VGKTSFLFRY ADDSFTSAFV
STVGIDFKVK TVFKNEKRIK LQIWDTAGQE RYRTITTAYY RGAMGFILMY DITNEESFNA
VQDWSTQIKT YSWDNAQVIL VGNKCDMEDE RVISTERGQH LGEQLGFEFF ETSAKDNINV
KQTFERLVDI ICDKMSESLE TDPAITAAKQ NTRLKETPPP PQPNCAC
//
