ID M3ZTI9_XIPMA Unreviewed; 547 AA.
AC M3ZTI9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Spermine oxidase {ECO:0000313|Ensembl:ENSXMAP00000005532.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000005532.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000005532.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000005532.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_005807188.1; XM_005807131.1.
DR AlphaFoldDB; M3ZTI9; -.
DR STRING; 8083.ENSXMAP00000005532; -.
DR Ensembl; ENSXMAT00000005538.2; ENSXMAP00000005532.2; ENSXMAG00000005505.2.
DR GeneID; 102226933; -.
DR KEGG; xma:102226933; -.
DR CTD; 54498; -.
DR eggNOG; KOG0685; Eukaryota.
DR GeneTree; ENSGT00940000157511; -.
DR HOGENOM; CLU_004498_2_3_1; -.
DR InParanoid; M3ZTI9; -.
DR OMA; EIMLLWE; -.
DR OrthoDB; 2642916at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR Gene3D; 3.90.660.10; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR PANTHER; PTHR10742:SF416; SPERMINE OXIDASE; 1.
DR Pfam; PF01593; Amino_oxidase; 2.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 34..269
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
FT DOMAIN 308..538
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 61671 MW; DAAF9EF99EA8C1A5 CRC64;
MQSCEISSDS TDDPLSSGFR PHRQPRIVVI GAGLAGLAAT RVLLKNGFTD VTVLEASDHI
GGRVQSVKNG EATLELGATW IHGANGNPVY HLAEENGMLE HTTDGERSVG RISLYTKNGV
AHYQTNVGKR IPKDLVEEFS DLYNEVYELT QEFFQNGKPV CAESQNSVGV FTRDLVRKRI
MVDPDDSEST KKLKLSMLQQ YLKVESCESS SPSMDEVSLS EFGEWTEIPG AHYVIPEGFM
KIVDLLAQDI PSHTICLCKP VRCIHWNYSA QHREVIGKGS HVKMEDNHND NNHSHQRNEE
PLILGQPIWV ECEDEEWIPA DHVIVTTSLG VLKQNHEAMF SPSLPEDKVL AIEKLGISTT
DKIFLEFEEP FWSPECNSIQ FVWEDEAQLE QLAYPEDLWY KKICSFDVLY PPERYGYMLS
GWICGQEALH MERCDDETVA ETCTKLLRRF TGNPDIPKPK RILRSSWGSN PYIRGSYSFT
RVGSSGQDCE RLAMPLPYAN STKAPPLQVL FAGEATHRKY YSTTHGALLS GQREATRLME
VYHDHKA
//
