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Database: UniProt
Entry: M4AEN0_XIPMA
LinkDB: M4AEN0_XIPMA
Original site: M4AEN0_XIPMA 
ID   M4AEN0_XIPMA            Unreviewed;      1840 AA.
AC   M4AEN0;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   25-OCT-2017, entry version 35.
DE   SubName: Full=Sodium channel, voltage-gated, type IV, alpha, b {ECO:0000313|Ensembl:ENSXMAP00000012924};
OS   Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae;
OC   Poeciliinae; Xiphophorus.
OX   NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000012924, ECO:0000313|Proteomes:UP000002852};
RN   [1] {ECO:0000313|Ensembl:ENSXMAP00000012924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000012924};
RA   Walter R., Schartl M., Warren W.;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSXMAP00000012924}
RP   IDENTIFICATION.
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000012924};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSXMAP00000012924}.
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DR   EMBL; AGAJ01014276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGAJ01014277; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 8083.ENSXMAP00000012924; -.
DR   Ensembl; ENSXMAT00000012940; ENSXMAP00000012924; ENSXMAG00000012780.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   GeneTree; ENSGT00830000128242; -.
DR   InParanoid; M4AEN0; -.
DR   OMA; GNDTWYG; -.
DR   OrthoDB; EOG091G00FK; -.
DR   Proteomes; UP000002852; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028817; Na_channel_a4suB.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   PANTHER; PTHR10037:SF186; PTHR10037:SF186; 2.
DR   Pfam; PF00520; Ion_trans; 4.
DR   Pfam; PF06512; Na_trans_assoc; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002852};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    134    152       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    195    216       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    228    249       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    255    275       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    397    424       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    503    520       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    623    641       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    653    671       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    691    712       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    733    761       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    823    846       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1064   1082       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1103   1121       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1141   1160       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1180   1206       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1305   1329       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1391   1409       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1421   1439       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1451   1471       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1508   1536       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      133    429       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      623    850       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      859   1057       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN     1062   1337       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1390   1585       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED       21     49       {ECO:0000256|SAM:Coils}.
FT   COILED      425    462       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1840 AA;  210627 MW;  D4078F4D9C8388F2 CRC64;
     MAPLLPPVGA EVFRRFTPAS LEEIQRRHEA EEKEQQIRKE QNIEIAEEDL PKPASDLEAG
     KPLPFIYGDP PAEFLNIPLE ELDPFYQSQK TFIVLSKGNV IYRFNAEPAC YVLSPFSPLR
     IFSIRILIHS IKTLFSLFIM VTILTNCVFM TMSDPPPWSK HAQYVFTGIY TFEATIKVLS
     RGFCMGDFTF LRDPWNWLDF MVISMAYLTE FVDLGNVSAL RTFRVLRALK TITVIPGLKT
     IVGALIQSVK KLRDVMILTV FCLSVFALIG LQLFMGNLRQ KCVLIPPLLR NDTSEGAFNI
     SFHENNSSDF EFYTHINNPD NYYYLPGQLD ALLCGNSSDA GTCPDGYMCL KAGRNPNYGY
     TSYDSFSWAF LSLFRLMTQD FWENLFHLTL RAAGKTYMIF FVVIIFLGSF YLINLILAVV
     AMAYAEQNEA NIAEAKQKEE EYAQILEALK QREEEVRCEE EKPPMTLQDK AEFFTASSQE
     GGALGESRPH ITKPRGAYEH GRYLDTVNIL GLLTLFLPFI KKKDSSFDLR IPLASLDTLK
     EFSTIQLSLP YMKLTEFTDY SKHLLCSDTF HITQQLSVSE FEDDQRPCPP CWYVFANIFL
     KWDCCGCWRW LKKLLYTIVM DPFVDLSITI CIVLNTVFMA MEHYPMTEQF EDLLSTGNLV
     FTGIFTAEMV LKLLAMDPYY YFQVGWNIFD SIIVTMSLVE LGLANVQGLS VLRSFRLMRV
     FKLAKSWPTL NMLIKIIGNS VGALGNLTLV LAIIVFIFAV VGMQLFGKSY KDCVCRIAQD
     CELPRWHMND FFHAFLIIFR VLCGEWIETM WDCMQVAGEP MCLIVFMMVL VIGNLVVLNL
     FLALLLSSFS GDNLAVTEDE GENNLQIAIN RISRGIAWTK AWFLNHIWSL VGKKTNVNSD
     ATGGSRLYLL TYKSVPCEEG EKSKEVLALT IVNSEQPMVQ VPKVDLSFLS SYYLNITSLK
     VPIAEAESDF DMPENEDDED EDEDNEEDDI EEQLSQGDES SVCSTVQRAP EVQKIEEVEE
     TPEDCYTEKC YNRCPCLDID TSQSKGKIWF NCRKTCFTIV EHNYFETFII FMILLSSGAL
     AFEDIYIEQR RVIKIILEYA DQVFTYVFVV EMILKWVAYG FKTYFTNAWC WLDFLIVDVS
     LVSLTANILG YSELGAIKSL RTLRALRPLR ALSRFEGMRV VVNALVGAIP SIFNVLLVCL
     IFWLIFSIMG VNLFAGKFYY CFNETSEEYF SPEEVNNKTQ CLDLIEKGFS EVRWKNTKIN
     FDNVGMGYLS LLQVSTFKGW MDIMYAAVDS REVESQPMYE DNLYMYMYFV CFIIFGSFFT
     LNLFIGVIID NFNQQKAKGV HLGGTDIFMT EEQKKYYNAM KKLGSKKPQK PVPRPTNKFQ
     GLVFDLVTKQ FFDILIMVLI CLNMVTMMVE TDEQSPEKEN ILYWVNLVFI VIFSTECCLK
     MIALRKHYFN VGWNIFDFVV VILSIVGLLL ADIIEKYFVS PTLFRVIRLA RIGRILRLIR
     GAKGIRTLLF ALMMSLPALF NIGLLLFLIM FIFSIFGMSN FAYVKKESMI DDIFNFESFG
     NSMICLFMIT TSAGWDGLLN PIMNTPPDCD PEFENPGTTV INVATEESAD PLSEDDFDMF
     YETWEKFDPR ASQFIHYSEL SDLCDVLQDP MRIPKPNTIK LIQMDLPLVP GDKIHCMDIL
     LALTAEVLGE SEAMDALKAT IEDKFMANNP TKKLYEPISN TLRKKHEELA AAVIQRAYRR
     HLLQRVIKLA SYKYRERTGG QRDDLSPPET EGFLCKRMDQ LYGDSETALV APELSSVQFD
     TETHKESDSG FLLMPQKKQI IMFPNSSSLH CSSLQSQDIC
//
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