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Database: UniProt
Entry: M4AHG9_XIPMA
LinkDB: M4AHG9_XIPMA
Original site: M4AHG9_XIPMA 
ID   M4AHG9_XIPMA            Unreviewed;      1979 AA.
AC   M4AHG9;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   22-NOV-2017, entry version 36.
DE   SubName: Full=Sodium channel, voltage-gated, type I like, alpha b {ECO:0000313|Ensembl:ENSXMAP00000013913};
OS   Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae;
OC   Poeciliinae; Xiphophorus.
OX   NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000013913, ECO:0000313|Proteomes:UP000002852};
RN   [1] {ECO:0000313|Ensembl:ENSXMAP00000013913}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000013913};
RA   Walter R., Schartl M., Warren W.;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSXMAP00000013913}
RP   IDENTIFICATION.
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000013913};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSXMAP00000013913}.
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DR   EMBL; AGAJ01023885; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGAJ01023886; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGAJ01023887; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 8083.ENSXMAP00000013913; -.
DR   Ensembl; ENSXMAT00000013931; ENSXMAP00000013913; ENSXMAG00000013864.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   GeneTree; ENSGT00830000128242; -.
DR   InParanoid; M4AHG9; -.
DR   OMA; CMSNHTT; -.
DR   OrthoDB; EOG091G00FK; -.
DR   Proteomes; UP000002852; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0006110; P:regulation of glycolytic process; IEA:Ensembl.
DR   GO; GO:0002082; P:regulation of oxidative phosphorylation; IEA:Ensembl.
DR   GO; GO:0036269; P:swimming behavior; IEA:Ensembl.
DR   GO; GO:0099536; P:synaptic signaling; IEA:Ensembl.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   InterPro; IPR024583; Na_trans_cytopl.
DR   Pfam; PF00520; Ion_trans; 4.
DR   Pfam; PF06512; Na_trans_assoc; 1.
DR   Pfam; PF11933; Na_trans_cytopl; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002852};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    125    148       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    196    216       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    254    287       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    293    309       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    402    429       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    757    775       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    787    810       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    822    846       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    867    895       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    957    980       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1223   1241       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1262   1281       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1293   1319       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1339   1365       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1462   1485       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1544   1562       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1574   1592       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1604   1624       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1661   1689       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      128    435       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      505    706       Na_trans_cytopl. {ECO:0000259|Pfam:
FT                                PF11933}.
FT   DOMAIN      757    984       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      994   1216       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN     1221   1493       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1543   1739       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      426    471       {ECO:0000256|SAM:Coils}.
FT   COILED      493    515       {ECO:0000256|SAM:Coils}.
FT   COILED     1950   1979       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1979 AA;  224616 MW;  621BDE84A9DBC20D CRC64;
     MAQLLVPPGP DSFRPFVPES LAAIERRIAE EEARRPRAER RSDDDDENGP KPNSDLEAGK
     SLPFIYGDIP PGLVSTPLED LDPFYSNQKT FIVLNRGKAI FRFNATSALY ILNPFNPLRR
     IAIKVLVHSM FSMLIMFTIL TNCAFMTLSN PPEWAKNVEY TFTGIYTFES LIKILARGFC
     VGKFTFLRDP WNWLDFSVIL MAYITEFVNL GNVSALRTFR VLRALKTISV IPALRTFRVL
     RALKTISVIP GKLCACACVC VCAGFLLTLF SCACLVQCCV FLCLFFLFEI NEMILQFISG
     LYWNLLYVSK NKMMVKWKEP NRSKCNYYHL PGRRDALLCG NGSGAGLCPE GFMCLKTGRN
     PDYGYTSFDT FSWAFLSLFR LMTQDFWENL YQQTLRAAGK PYMIFFVLVI FLGSFYLINL
     ILAVVAMAYD EQNQATIEEA QQKEEEFQAM LEQLKRQQEE AQVAAAAATE SGEYSGRGGP
     TSESSSGTSK LSSKSAKERR NRRKKRKQRE EEEERAVCDK FHKSMSEDSI KRSSFRFSID
     ANRLSYEKRC SSPNQSLLSV RGSLFSPRRN SRASLFSFRG RARDMGSEND FADDEHSTFE
     ENDSRRGSLF LPRRLERRCS AVSQTSLGAP RIVLPANGKM HCSVDCNGVV SLVGGTPVTT
     SPVGLLLPEG TTTDTEIKKR RSGFLQPSMD YLDEPGGRQR AMSVASILTN TMEELEESRQ
     KCPPCWYRFA NTCLIWDCCP AWLKIKEFVS MVVMDPFVDL AITICIVLNT LFMAMEHYPM
     TREFDNLLSI GNLVFTGIFT AEMCFKIIAL DPYYYFQEGW NIFDGIIVSL SLMELGLANV
     EGLSVLRSFR LLRVFKLAKS WPTLNMLIKI IGNSVGALGN LTLVLAIIVF IFAVVGMQLF
     GKSYKECVCK ISDNCELPRW HMHDFFHSFL IVFRVLCGEW IETMWDCMEV AGQTMCIIVF
     MMVMVIGNLV VLNLFLALLL SSFSADNLAA TDDDSEMNNL QIAVGRIQRG ISYVKTKVRQ
     FLQSLCFNGG KGSGLAEESK PLDDLQSNGK GNCISNHTPL EITKDPSGVY MMEGNGKPGG
     LVVGVGGDTT SKYPMEECDY MSFIHNPSLT VTVPIAVGES DFENLNTEDF SSDSSDVEGS
     KEKLDIEPQP LSSSEGSTVD IRPPGDGAES VELEPEESLD PEACFTEGCV SRFQCCQVSE
     EVGWFKSWWT LRKTCFIIVE HNWFESFIIF MILLSSGALA FEDVYIEQRR TIKTVLEYAD
     KVFTYIFILE MLLKWVAYGF VKYFTNAWCW LDFLIVDVSL VSLVANALGY SELSAIKTLR
     TLRALRPLRA LSRFEGMRVV VNALLGAIPS IMNVLLVCLI FWLIFSIMGV NLFAGKYYHC
     INTTTDELFP ISVVNNRTEC LNLVNNSARW KNVKINFDNV GAGYLALLQV ATFKGWMDIM
     YAAVDSRNLE EQPDYEVNLY MYLYFVIFII FGSFFTLNLF IGVIIDNFNQ QKKKFGGQDI
     FMTEEQKKYY NAMKKLGSKK PQKPIPRPTN AFQGFVFDCV TKQAFDIVIM ILICLNMVTM
     MVETDDQTKE MDKILYWINL VFIVLFTGEC ALKMISLRHF YFTVGWNIFD FVVVILSIVG
     MFLSEVIEKY FVSPTLFRVI RLARIGRILR LIKGAKGIRT LLFALMMSLP ALFNIGLLLF
     LVMFIYAIFA MSNFAYVKRE SGIDDMFNFE TFGNSMICLF QITTSAGWDG LLAPILNKRE
     PDCDSKIEHP GNSYSVATEE SAEPLSEDDF EMFYEVWERF DPDATQFVEY NKLSEFADAL
     DPPLRIAKPN MIQLIAMDLP MVSGERIHCL DILFAFTKRV LGEGGEMDML RGQMEERFMA
     SNPSKVSYEP ITTTLRRKQE EMSAIVIQRA FRRYMIQQAM KKASALYKEQ LKEGVRDPDK
     DVMVISKFNE NSTSDKTDMT PSTASPPSYN SVTKSDKDKY EKENREKENK GKDLKDRKK
//
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