ID M4AKG2_XIPMA Unreviewed; 321 AA.
AC M4AKG2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Fumarylacetoacetate hydrolase domain-containing protein 2-like {ECO:0000313|Ensembl:ENSXMAP00000014956.1};
GN Name=FAHD2A {ECO:0000313|Ensembl:ENSXMAP00000014956.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000014956.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000014956.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000014956.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May have hydrolase activity. {ECO:0000256|ARBA:ARBA00037111}.
CC -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
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DR AlphaFoldDB; M4AKG2; -.
DR Ensembl; ENSXMAT00000014976.2; ENSXMAP00000014956.1; ENSXMAG00000014921.2.
DR eggNOG; KOG1535; Eukaryota.
DR GeneTree; ENSGT00940000160571; -.
DR HOGENOM; CLU_028458_3_2_1; -.
DR OrthoDB; 9433at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR PANTHER; PTHR42796:SF4; FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A; 1.
DR PANTHER; PTHR42796; FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 114..321
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 321 AA; 35354 MW; B611956AA46F19A5 CRC64;
MRIPLRSCCI FRSFISQKQT LDTQRRGLSG AAMRLVQFRC RGDGDDVRVG VEQGQGLNVV
DLKAFDSSMP STVRELLQLG DKGLECAQRA LASGKFVVER ANIQLLSPIL APEKVVCVGM
NYRDHCLEQN APIPEEPIIF SKFPSAITGP YDHIILPTES QEVDWEVELA FVIGRRGKHI
KESDALSHVA GFAVANDVSA RDWQFKRNGK QWLLSKTFDS FCPLGPALVT IDAVKDPHNL
GIRCLVNGDT VQSSNTSQMI FKTAELIAWV SKFVTLTPGD VFLTGTPPGV GVFRNPPVFL
KRGDTVECQI DQIGSIINKV V
//
