ID M4AWJ7_XIPMA Unreviewed; 1175 AA.
AC M4AWJ7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Laminin subunit beta 3 {ECO:0000313|Ensembl:ENSXMAP00000018842.2};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000018842.2, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000018842.2}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000018842.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR RefSeq; XP_014330136.1; XM_014474650.1.
DR AlphaFoldDB; M4AWJ7; -.
DR STRING; 8083.ENSXMAP00000018842; -.
DR Ensembl; ENSXMAT00000018870.2; ENSXMAP00000018842.2; ENSXMAG00000018790.2.
DR GeneID; 102232579; -.
DR KEGG; xma:102232579; -.
DR CTD; 3914; -.
DR eggNOG; KOG0994; Eukaryota.
DR GeneTree; ENSGT00940000165244; -.
DR HOGENOM; CLU_001560_0_0_1; -.
DR InParanoid; M4AWJ7; -.
DR OMA; RCLCLPH; -.
DR OrthoDB; 90222at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00055; EGF_Lam; 6.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF268; LAMININ SUBUNIT BETA-3; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 6.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00180; EGF_Lam; 6.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01248; EGF_LAM_1; 2.
DR PROSITE; PS50027; EGF_LAM_2; 5.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1175
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017380311"
FT DOMAIN 32..257
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 323..385
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 386..437
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 438..486
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 487..534
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 535..581
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT COILED 839..898
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1043..1070
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 353..362
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 408..417
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 438..450
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 440..457
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 459..468
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 487..499
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 489..506
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 508..517
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 535..547
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 537..554
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 556..565
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1175 AA; 128330 MW; CE453AE10B84C642 CRC64;
MLGFPLPQES RMRILLLLTA AAAVAAAQND CSLGACYPPS TDLLLGRSHQ LRASSTCGLT
DSEIYCTPFQ WRMKCCPCDS RNPNGPLAHT VQDILTTSGP NRWWQSSKGV DPVILQFDLN
NLFQLDNLML SFKGPRPKAL LIERTLDNGR TWQPALYLAK NCEEAFPGIQ TNSPISLEQT
YCHALRPHAD PFQEETIEFS PLRPYLFAPV SNSQKIEDKA GLTGLRVTLT ELGDVPHFPG
RSFSKFFALK EMRVMGTCMC HGHADRCQAQ EYNYPGTDTI QVNHVCDCRH NTAGENCERC
ADFYNDLPWR PAEEGNTHTC QRCDCNNHAQ RCHFDPAVYE ASGRRSGGVC EGCMHHTTGP
KCDRCARGYQ PNPRSRMDRP DACIRCACNA EGTVNGGQCE DSAGSCPCKA NVEGPHCDRC
RKGFHSLSSS DPMGCKKCSC SPVGSLSTLC DPVTGQCPCR PHFHGPTCDV CSKGYWKPPQ
SDVCEPCGCD PTGSTSDTCD QRTGQCRCRR DFGGRTCSQC ADGSYGTPLS GCRPCPCDTA
GTLPEVCNRK TGECLCRPGA TGPRCDSCSR GYCDSFPACE LCPNCFFTLD SQRRNVSLAL
DKLSFRLPSL PGGGGDLGSF GPRFRELEAG LGRIRESVSR PPKTVTQLDD ALFLLNKLRD
DLEKVDDNLP PPVRDPGLEA ELDKLQALLD SIALIYEAKK DSTGAVTDPD DAEGLDVIKK
AYDESTDAAK KVNSTENTIK EARDIQEEAE GVQNRVQPNN TRDLSQLKNN MASQPDLTPV
AKQVCGSARS EPCTPLRCEG DALCPPEGSP LCQNGAQCVG ALPISKRADA DVTDVKDRLA
NLSLKITEAA EMLQNAQEKS DEVRQVVKDL SGKTKTARDR LEDDLQETRN IIQDLKDFLT
DPSSNLTQVQ EISEWILNAN LPVSLPALEK KLEELKNLAA SLPNTENVLK EAKPQLDTAR
KLLQEADAAR VKALGTKDDL DKLLKGLDAG NDSFSDLEEK LQGSLDLIDS VRDDLTQVED
TLKPAEKALT DTEALTTPMK DQLEELKKLL EDAKRKAPDA LQTAGKAEEE AAAAQPILKS
LEEQLDRLKG QASPGAPGET SPLAERVEKL KEKAKTLTNT TLSMTDALEG KADTLRGLQD
EIIQKSAKLE GLDAKLKDIL QAIRKRADDL RTCSA
//
