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Database: UniProt
Entry: M4AZS2_XIPMA
LinkDB: M4AZS2_XIPMA
Original site: M4AZS2_XIPMA 
ID   M4AZS2_XIPMA            Unreviewed;       498 AA.
AC   M4AZS2;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   28-MAR-2018, entry version 43.
DE   SubName: Full=Potassium voltage-gated channel, shaker-related subfamily, member 2a {ECO:0000313|Ensembl:ENSXMAP00000019967};
OS   Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae;
OC   Poeciliinae; Xiphophorus.
OX   NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000019967, ECO:0000313|Proteomes:UP000002852};
RN   [1] {ECO:0000313|Ensembl:ENSXMAP00000019967}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000019967};
RA   Walter R., Schartl M., Warren W.;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSXMAP00000019967}
RP   IDENTIFICATION.
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000019967};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
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DR   EMBL; AGAJ01038934; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005814552.1; XM_005814495.2.
DR   STRING; 8083.ENSXMAP00000019967; -.
DR   Ensembl; ENSXMAT00000019995; ENSXMAP00000019967; ENSXMAG00000019918.
DR   KEGG; xma:102217218; -.
DR   CTD; 3737; -.
DR   eggNOG; KOG1545; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00760000118846; -.
DR   KO; K04875; -.
DR   OMA; DFQEENL; -.
DR   OrthoDB; EOG091G10NU; -.
DR   Proteomes; UP000002852; Unassembled WGS sequence.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR   InterPro; IPR004049; K_chnl_volt-dep_Kv1.2.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   PANTHER; PTHR11537:SF23; PTHR11537:SF23; 1.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01509; KV12CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01496; SHAKERCHANEL.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002852};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00984201}.
FT   TRANSMEM    163    187       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    222    243       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    250    268       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    328    349       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    389    410       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       32    132       BTB. {ECO:0000259|SMART:SM00225}.
SQ   SEQUENCE   498 AA;  56624 MW;  484A01CB663BEE74 CRC64;
     MTVATGDPSD EAAAHPGHPL DYDPEADHEC CERVVINISG LRFETQLKTL SQFPETLLGD
     PKKRMRYFDP LRNEYFFDRN RPSFDAILYY YQSGGRLRRP VNVTLDIFSE EIRFYELGEE
     AIEMFREDEG FIKEEERPLP DNEFQRQVWL LFEYPESSGP ARIIAIISVM VILISIVSFC
     LETLPIFRND EEDMHKSHAQ VFSPETNSTI ISYTSTYFTD PFFVLETLCI IWFSFEFLVR
     FFACPSKAGF FGNIMNIIDI VAIIPYFITL GTELADRAED GQPGQQAMSL AILRVIRLVR
     VFRIFKLSRH SKGLQILGQT LKASMRELGL LIFFLFIGVI LFSSAVYFAE ADEPESQFES
     IPDAFWWAVV SMTTVGYGDM VPTTIGGKIV GSLCAIAGVL TIALPVPVIV SNFNYFYHRE
     TEGEEQAQYL QVNVPKADSG EELKKSRSGS TISKSDYMEI QEAVNNSNED FQEENLKTAN
     CTLANTNYVN ITKMLTDV
//
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