ID   M4B3N9_HYAAE            Unreviewed;       896 AA.
AC   M4B3N9;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
OS   Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS   (Peronospora arabidopsidis).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Hyaloperonospora.
OX   NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP800888, ECO:0000313|Proteomes:UP000011713};
RN   [1] {ECO:0000313|Proteomes:UP000011713}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX   PubMed=21148394; DOI=10.1126/science.1195203;
RA   Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA   Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA   Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA   Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA   Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA   Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA   Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA   Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA   Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA   Tyler B.M.;
RT   "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT   arabidopsidis genome.";
RL   Science 330:1549-1551(2010).
RN   [2] {ECO:0000313|EnsemblProtists:HpaP800888}
RP   IDENTIFICATION.
RC   STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP800888};
RG   EnsemblProtists;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; JH598179; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M4B3N9; -.
DR   STRING; 559515.M4B3N9; -.
DR   EnsemblProtists; HpaT800888; HpaP800888; HpaG800888.
DR   VEuPathDB; FungiDB:HpaG800888; -.
DR   eggNOG; KOG1474; Eukaryota.
DR   HOGENOM; CLU_015264_0_0_1; -.
DR   InParanoid; M4B3N9; -.
DR   OMA; NENSRFM; -.
DR   Proteomes; UP000011713; Unassembled WGS sequence.
DR   Gene3D; 1.20.1270.220; -; 1.
DR   Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR   InterPro; IPR001487; Bromodomain.
DR   InterPro; IPR036427; Bromodomain-like_sf.
DR   InterPro; IPR018359; Bromodomain_CS.
DR   InterPro; IPR027353; NET_dom.
DR   InterPro; IPR038336; NET_sf.
DR   PANTHER; PTHR45926:SF6; HOMEOTIC PROTEIN FEMALE STERILE-RELATED; 1.
DR   PANTHER; PTHR45926; OSJNBA0053K19.4 PROTEIN; 1.
DR   Pfam; PF17035; BET; 1.
DR   Pfam; PF00439; Bromodomain; 1.
DR   PRINTS; PR00503; BROMODOMAIN.
DR   SMART; SM00297; BROMO; 1.
DR   SUPFAM; SSF47370; Bromodomain; 1.
DR   PROSITE; PS00633; BROMODOMAIN_1; 1.
DR   PROSITE; PS50014; BROMODOMAIN_2; 1.
PE   4: Predicted;
KW   Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011713}.
FT   DOMAIN          365..437
FT                   /note="Bromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50014"
FT   REGION          637..840
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        654..671
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        673..689
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        732..746
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        767..793
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        794..840
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   896 AA;  98595 MW;  E00BE43A72C5E87C CRC64;
     MVKEQAQKPV LATVKQELHG KAVEPPLPAA AKYQSNMPST ATAAVATVKT EQVEAEFLVD
     SSKTKESALG LPREVLQYAP LLVGKYYIRD KHAVWSGMWG MNEAAFGPSG ITSVFEMRSQ
     EDVAIPICSG TADVVHPAMA TLALARSSQT SNAVACEVSP VYWGYETNAE VRSAMPFDGK
     YSGSFQIQAM KGKPQTVTEH DVEIRFVHDV GSPSQFVVFG SGENRFGQFT LHGCLAKETN
     ELRLYKVYKP KDPVKRALPR RARTVRASIP AKREAKALSI SAPGVAAIVA SVDVTKSAIP
     SVTPAFIAPR KVSTPRLDYA SPSLILGRSE RKRSIPAHLR EDNILEFDHA PMSMKKCLSV
     LKGLMSNPKS APFMVPVDPV ALGIPDYFHV IKDPMDLGTI RNNLEMGFYD SPTEFADHVR
     LVFQNAMLYN AAHSQVHIYA NKLMDDFEKR YKGLNVKLST KSKYPDLKLK KDRKVDAAFS
     SKKIRGGKGT KGNTKRRGHD TGLIMSLKED IERLKATLEQ LQPGVAKGGS CKLSKTVTRP
     FKMEDLTEEE LNEPMSHLDK ARLSSDIKLL PQDKINRVLQ IIAEAVPENG IGRKRKRPAK
     KAKLAPAEKR LKSAEVAALN IQHRQEELRS QLAAIDSGGA SVGHSTPGNA GDRRSDQDVT
     KDVHADTDGV KKGGDSSSGS SSSPSESSDS DSDSDSESDS DDGGAPLERS PPLASAPSLS
     QLDPSASVHA VDAAKKIRDE QLASSEPLRV ENRGAWSMLA KKETPNGTPL CHSNGGNQSS
     SLWLSARSME QIKQQKIQQK EKERTDELEV LKRRESEQRD KEKEREQAER RKQEKEQLAK
     LAEEKRLREE RVRDAERVRL AQLAMEHEKL VRDDDVELHD ATLSEDLDAF SSSSFL
//