ID M4BAF5_HYAAE Unreviewed; 553 AA.
AC M4BAF5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE RecName: Full=Xaa-Pro aminopeptidase P {ECO:0008006|Google:ProtNLM};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP803265, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP803265}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP803265};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; JH598070; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4BAF5; -.
DR STRING; 559515.M4BAF5; -.
DR EnsemblProtists; HpaT803265; HpaP803265; HpaG803265.
DR VEuPathDB; FungiDB:HpaG803265; -.
DR eggNOG; KOG2413; Eukaryota.
DR HOGENOM; CLU_011781_2_1_1; -.
DR InParanoid; M4BAF5; -.
DR OMA; LVDQAWG; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011713}.
FT DOMAIN 66..114
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 305..523
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 553 AA; 61295 MW; 30F90A50289D246E CRC64;
MLAPNKLREL RALMSRTNVR LLPLRHRLGK TEKEEAAVEP TIQSLQAFIV DTADAHQSEY
VGDAHKRREF LTGFTGSSGT ALVTMNEALM WTDGRYFLQA EQELSEDWTL MKSEEPGVPT
IEDTKIELVA LHETENLIDR VWTDRPAISP SQITFLSEKY TGRSVADKLT RLREAVKEEG
ADAVVLTALD DIAWLFNIRG NEVKFNPVVT SYAIVTSDSA ILFLNASNED EVTQHLGSSG
IVCKPYSNML KELSAFTSAN KGKQILVDPA QCNVAVFLAI PAVNRKEVMS VVMAQKAIKN
ATEIEGMRQA HIRDGAALVK YFCWLENEMD SSHKDRWDEV MVADKQEQLR QQVKDFVSLS
FDTISSIGAN GAIIHYSPKR GNCAKMSTSA MYLNDSGAQY LDGTTDVTRT LHFGHPTSYE
KACFTYVLKA HIALASTVFP DKIEGVRLDA VARAPLWKAG LDYRHGTGHG VGAFLNVHEK
GVLMSFRLNP NGLKIQDGMI LSNEPGYYED GKFGIRIESI MVAQKVSCSS CASLSVVMCI
RDALLTACLY LYV
//
