ID M4BD96_HYAAE Unreviewed; 449 AA.
AC M4BD96;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Glutaredoxin domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP804263, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP804263}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP804263};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; JH598152; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4BD96; -.
DR STRING; 559515.M4BD96; -.
DR EnsemblProtists; HpaT804263; HpaP804263; HpaG804263.
DR VEuPathDB; FungiDB:HpaG804263; -.
DR eggNOG; KOG0911; Eukaryota.
DR HOGENOM; CLU_026126_12_2_1; -.
DR InParanoid; M4BD96; -.
DR OMA; HDIVMEL; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02066; GRX_family; 1.
DR CDD; cd03028; GRX_PICOT_like; 2.
DR Gene3D; 3.40.30.10; Glutaredoxin; 4.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR033658; GRX_PICOT-like.
DR InterPro; IPR004480; Monothiol_GRX-rel.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR NCBIfam; TIGR00365; Grx4 family monothiol glutaredoxin; 2.
DR PANTHER; PTHR10293; GLUTAREDOXIN FAMILY MEMBER; 1.
DR PANTHER; PTHR10293:SF73; GLUTAREDOXIN-3; 1.
DR Pfam; PF00462; Glutaredoxin; 3.
DR Pfam; PF00085; Thioredoxin; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 4.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 3.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713}.
FT DOMAIN 13..106
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|Pfam:PF00085"
FT DOMAIN 152..216
FT /note="Glutaredoxin"
FT /evidence="ECO:0000259|Pfam:PF00462"
FT DOMAIN 261..325
FT /note="Glutaredoxin"
FT /evidence="ECO:0000259|Pfam:PF00462"
FT DOMAIN 365..429
FT /note="Glutaredoxin"
FT /evidence="ECO:0000259|Pfam:PF00462"
SQ SEQUENCE 449 AA; 49691 MW; 7E71E1A816300D09 CRC64;
MAAVTGSVSN VQSVAQFDDA VARDSTLSVT YFYAEFHDAC RPNGQLDVVL RQLATLYPRV
RFLKVAAEEL PDLSDRFLVT VVPTFVIAQG SVVLEKLEGT NVAVLAKRVD VLNSRVVHTT
TTSTSAANET LSKPLDGTRQ DRLAKLLYAA PVMLFLKGTP SEPKCDASRD VVVLLNEEEI
AFSTFDVLQD QDVQEGLKLV SKSSMFPQLY VNSSFIGGLE VLKEIKAKGS IADHIGVTKK
LEPTDAAFQA SLRALVNSAP VLLFMKGTPS DPKCGFSKKT VQLLRDHEIA FSYFDILSDA
QVRQGLKQFA NWPTYPQLYV KGKLVGGLDI LNEMAEDGDL SEQLGVEKKT KKENKYEQLI
NRARVMIFIK GTPQQPQCGF SRKLVDILNS EGFKYDSFDI LTDDSVRQGL KKYSNWPTFP
QLYVKGELVG GLDIVQQMQE DGELAELKE
//
