ID   M4BHX1_HYAAE            Unreviewed;      1049 AA.
AC   M4BHX1;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   28-JUN-2023, entry version 31.
DE   RecName: Full=BEACH domain-containing protein {ECO:0000259|PROSITE:PS50197};
OS   Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS   (Peronospora arabidopsidis).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Hyaloperonospora.
OX   NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP805997, ECO:0000313|Proteomes:UP000011713};
RN   [1] {ECO:0000313|Proteomes:UP000011713}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX   PubMed=21148394; DOI=10.1126/science.1195203;
RA   Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA   Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA   Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA   Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA   Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA   Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA   Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA   Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA   Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA   Tyler B.M.;
RT   "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT   arabidopsidis genome.";
RL   Science 330:1549-1551(2010).
RN   [2] {ECO:0000313|EnsemblProtists:HpaP805997}
RP   IDENTIFICATION.
RC   STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP805997};
RG   EnsemblProtists;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; JH598269; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M4BHX1; -.
DR   STRING; 559515.M4BHX1; -.
DR   EnsemblProtists; HpaT805997; HpaP805997; HpaG805997.
DR   VEuPathDB; FungiDB:HpaG805997; -.
DR   eggNOG; KOG1786; Eukaryota.
DR   HOGENOM; CLU_291262_0_0_1; -.
DR   InParanoid; M4BHX1; -.
DR   Proteomes; UP000011713; Unassembled WGS sequence.
DR   Gene3D; 1.10.1540.10; BEACH domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR000409; BEACH_dom.
DR   InterPro; IPR036372; BEACH_dom_sf.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   PANTHER; PTHR44662; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR   PANTHER; PTHR44662:SF1; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR   Pfam; PF02138; Beach; 1.
DR   SUPFAM; SSF81837; BEACH domain; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50197; BEACH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011713}.
FT   DOMAIN          1..114
FT                   /note="BEACH"
FT                   /evidence="ECO:0000259|PROSITE:PS50197"
FT   REGION          222..273
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          307..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          343..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          396..424
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        234..252
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        405..419
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1049 AA;  112356 MW;  D0C90CADB37DC828 CRC64;
     MDDLQVPIWS DVNGDDVASV FVRHHRAMLE SDRVSALLHK WIDLNFGAAL NGATAIREKN
     VPLVVHAANK SPGFVQLFTD PHPRRICCCP GQKQQEPKIQ STVDLAGMKT NSPRAALRPP
     GYTRKEVNAM LSRAMQVVTD TQKDGECLSS SIGGTASGGM SVMGGGGRAG GREVEVSRLG
     LLQGQASVES AAGTSGAAGT NYGGIAAASP NEATRSQIIM RNLKQRRRGN KSRARSQLNG
     AGADSTPPPS TLMLHSGRDA LSPPVSGSTG MSSSRLGHLF HLDSNNNNNN SSTHGVLPIP
     LETSVSPPNS MESGTSFGNN ANSRSLTTTG SLTEHLRVLT ISTPQSVSTN VNRESGGSTG
     GRGSLSHHTR HSSLGSDGSN TGSHLLRDLW QQLRQPEDDG SLGTSIVGGQ GNSQAHGHHR
     SGSAGHELAL ALGGTAGDMQ LSDLDAANDI DPAVDVFGSL DDVDLKLLQL GLPIVLCGDE
     KEPKVDADDD THGLEAEASR ANEQQAVADA IVDPIYRIPD ELVSHTAQLA LFQRAQAADI
     FSMGCIAAEL YTHKPVFSRR SLEDYLFAYS KQQKQDSSEN VIAQADGWIS GILAAQCSAK
     VSQHQLPWNY ALSERLVGLP LNLKQAVLDM LHPDPHERLL LASKIDGLEA VVLDKSTCAT
     SSKACVPSTL SPDTFRAAPS ALFPKDMVMV YKFLTKLHSI PERDWHSRFT AARHLLSSLS
     GLSEIHFRVA MPELVRCFRA KSHTETICAE RVAAAVIFLL PEMARQLGRG RARIELLPDV
     VRVYESSELG RSSLLRCCLG APSVLLSLLR AFGAAVVLDS IVPVVLEWLV PPVAADTDAE
     LRSSLTSLSR RAPPPLPFAA ESAALTAVTF GELSSSAMLG PSLTAKYLLP ALLTQLGHVK
     NRWTHLADNK TLRRTDNKGS VAPALSEDSE SHRSAEFHIT FLSKSKLYES HHVADAVLQV
     CRELGEFPLA NMLLPRLLEV LPRLISLSEK IGSVRIEGVP VRTLALGLYL LLLDIATLTS
     RTNLVRTGRA GARNLRVAAH SQTRDPYAE
//