ID M4BQ08_HYAAE Unreviewed; 1007 AA.
AC M4BQ08;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Vacuolar protein sorting-associated protein 11 homolog {ECO:0000256|PIRNR:PIRNR007860};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP808497, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP808497}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP808497};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the VPS11 family.
CC {ECO:0000256|ARBA:ARBA00007070, ECO:0000256|PIRNR:PIRNR007860}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH598544; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4BQ08; -.
DR STRING; 559515.M4BQ08; -.
DR EnsemblProtists; HpaT808497; HpaP808497; HpaG808497.
DR VEuPathDB; FungiDB:HpaG808497; -.
DR eggNOG; KOG2114; Eukaryota.
DR HOGENOM; CLU_001287_0_1_1; -.
DR InParanoid; M4BQ08; -.
DR OMA; ENECPAC; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd16688; RING-H2_Vps11; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR016528; VPS11.
DR InterPro; IPR024763; VPS11_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23323:SF24; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG; 1.
DR Pfam; PF12451; VPS11_C; 1.
DR PIRSF; PIRSF007860; VPS11; 4.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50236; CHCR; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR007860};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 905..941
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT COILED 862..896
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1007 AA; 114094 MW; 4F784679CFE2ADCA CRC64;
MAQWRRFAFF DKEVLKDANG PWMKGVDITS MSANRGLICV GDADGYVHLA NRSLEARKFQ
AHELFVSHVV MMKRSNVLAT IGDGIDPRPD ELREQSKAIA EAGRAPNAEE PTGKSTAVVR
FWRTDLQDRE GKPKLLQQIP IFAKKYPEEA VTAFAVNDDL SQFAVGLKNG AVILFRSDLK
RRTDRPSHLL QPAGQYPVTG LSFISKPVTA TSVHVFLYAS TRRGLTCYHC SHDDPALVKS
VGGAAALPPR TTVLDERGVD VNCSCVNEED EIAVGQTDAV YFYTTEDRSV CFAFEGEKKY
LHFFKHYLLV AHIDPRGRHQ VNVYDLQNKF IAFNWTLTST NPKGPMRKPP LASNSRTADA
RFGLDEMEEV RHVVCEFGAI FVVSSMGHVY RLSEKDTTSK LEILFRKNLY SIAISLAFSS
NYDVNSIIDI FRMYGDHLYQ KGDYDGSLRQ YVRTIGHVEP SYVIRRFLDA QRIHNLTAYL
EALHEKAFAN AEHTTLLLNC YTKLKDVKKL DKFIQLDEVI DAKKTNGTKI DNDASDLALK
DGGGAANLNF DVETAISVLW ENYPQHALTL ARKHEEHSWY LKIQLGQISY VDSEDSAALS
ESEKERVADA LEYIQHLSFS EADSNLRKYG RTLVTHMPGP ATELLKRLCT GKYVPEDPSL
KSDPGDFLHL FVSHRAQLKE FLQYIVEVET VSNTSIGNTL LEMVLSDDDE GENGGRSVEE
KEESVLRILD NPRVKYDEDH ALIHLQMRGM KKGKRYLYNK LHMYHMLVQF HIEENDDQSI
LEEVRKHGDK DPNLWSLALK YFAERGPLPK GATSGKEWEE LQQLLVLIDT NSAIPPLQVV
QVLSQSRELP VSVIKQYVVN QLASDEKKIE EDEEKIKAFR SDTKQMKEEI AQLSSRAVVF
QATKCDLCSH DLDLPAVHFM CQHSFHLNCI SETDRECISC SMDHRHILGL KTQLEQKAGN
HEQFYNQLET AADGFNTIAE YFGKGIFKSN EVVLDEGSFE TRFSAEF
//
