ID M4C425_HYAAE Unreviewed; 727 AA.
AC M4C425;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=U3 small nucleolar RNA-associated protein 15 C-terminal domain-containing protein {ECO:0000259|Pfam:PF09384};
OS Hyaloperonospora arabidopsidis (strain Emoy2) (Downy mildew agent)
OS (Peronospora arabidopsidis).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Hyaloperonospora.
OX NCBI_TaxID=559515 {ECO:0000313|EnsemblProtists:HpaP813843, ECO:0000313|Proteomes:UP000011713};
RN [1] {ECO:0000313|Proteomes:UP000011713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Emoy2 {ECO:0000313|Proteomes:UP000011713};
RX PubMed=21148394; DOI=10.1126/science.1195203;
RA Baxter L., Tripathy S., Ishaque N., Boot N., Cabral A., Kemen E.,
RA Thines M., Ah-Fong A., Anderson R., Badejoko W., Bittner-Eddy P.,
RA Boore J.L., Chibucos M.C., Coates M., Dehal P., Delehaunty K., Dong S.,
RA Downton P., Dumas B., Fabro G., Fronick C., Fuerstenberg S.I., Fulton L.,
RA Gaulin E., Govers F., Hughes L., Humphray S., Jiang R.H., Judelson H.,
RA Kamoun S., Kyung K., Meijer H., Minx P., Morris P., Nelson J.,
RA Phuntumart V., Qutob D., Rehmany A., Rougon-Cardoso A., Ryden P.,
RA Torto-Alalibo T., Studholme D., Wang Y., Win J., Wood J., Clifton S.W.,
RA Rogers J., Van den Ackerveken G., Jones J.D., McDowell J.M., Beynon J.,
RA Tyler B.M.;
RT "Signatures of adaptation to obligate biotrophy in the Hyaloperonospora
RT arabidopsidis genome.";
RL Science 330:1549-1551(2010).
RN [2] {ECO:0000313|EnsemblProtists:HpaP813843}
RP IDENTIFICATION.
RC STRAIN=Emoy2 {ECO:0000313|EnsemblProtists:HpaP813843};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; ABWE02002914; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M4C425; -.
DR STRING; 559515.M4C425; -.
DR EnsemblProtists; HpaT813843; HpaP813843; HpaG813843.
DR VEuPathDB; FungiDB:HpaG813843; -.
DR eggNOG; KOG0310; Eukaryota.
DR HOGENOM; CLU_021102_4_0_1; -.
DR InParanoid; M4C425; -.
DR OMA; XPEDETI; -.
DR Proteomes; UP000011713; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR018983; U3_snoRNA-assocProt_15_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19924:SF26; U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG; 1.
DR PANTHER; PTHR19924; UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER; 1.
DR Pfam; PF09384; UTP15_C; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011713};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..727
FT /note="U3 small nucleolar RNA-associated protein 15 C-
FT terminal domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004049210"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 334..375
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 376..418
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 465..506
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 570..712
FT /note="U3 small nucleolar RNA-associated protein 15 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF09384"
SQ SEQUENCE 727 AA; 79841 MW; DD28FC0C713D252F CRC64;
MVVFGVLAAI AFTFRAKMKT YDEAAYPVDD REVVVANTFN QVYCYAEGYH YCNNATAKEA
YTTFFPDAPS ELLGLLPNVT GIVSLCGQHS STVSGLQTVC EACNMSTTFA KYDRVLTWAE
DKCPRTAVTG QWCASFLATG APGEVYNGAP YGQCRAIFFG VAIDWSTTMA TAGVLLAVAA
LVIIIMTCFT RRSRERVTYN HDEDEGTTGI AVPMATSGEF KRLVLKQFPP TNEVETAEST
YWKKFHAPEE IQQVGAVTHI DVSPVTPHQV AITSSTRIHL YSTTTNAIVK TFSRFRDVVY
SGTFRSDGKL LVAGGEAPFV QILDTNTRAI LRSLKGHSGA IRSTRFALDN VHVLSCSDDK
TARYWDLPTG KPLALLGDHT DYVRSSAANP SSHNVWATGS YDHTVKLWDL RTSDQSVSKS
TTSLDHGAPV ETCMIMPGGS LLLSAGGNTI KVWDILSGGR LLHSFSSHQK TITSLGLDGT
GTRLMSGSLD GHLKVYDLKT YELSHGFKYN SGVLTFGMSP TNGHLFAGTV DGVLSVRRRP
VKRTELNETR TRQAVIRGGT YKYFLRGKNA KPAAADFLVA TTRHKRIQPY DQALRKFDYK
KALNEALDTR SPVIVASMLE ELRLRVGLKR ALGNRDEESL EPLLAFLIKY VTDPKYALLL
VHVCTIVCDL YAPKLSQSML IDGLFIKLHE KLNEELRDQR QVLAVVGMMD SLMAAQTNGA
VSVEDSN
//
