ID M4ISH3_9PEZI Unreviewed; 136 AA.
AC M4ISH3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Beta-tubulin {ECO:0000313|EMBL:AGA18194.1};
DE Flags: Fragment;
OS Xylaria sp. 5327.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Xylaria.
OX NCBI_TaxID=1235929 {ECO:0000313|EMBL:AGA18194.1};
RN [1] {ECO:0000313|EMBL:AGA18194.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=5327 {ECO:0000313|EMBL:AGA18194.1};
RX PubMed=23472167;
RA Chen J., Zhang L.C., Xing Y.M., Wang Y.Q., Xing X.K., Zhang D.W.,
RA Liang H.Q., Guo S.X.;
RT "Diversity and taxonomy of endophytic xylariaceous fungi from medicinal
RT plants of dendrobium (orchidaceae).";
RL PLoS ONE 8:E58268-E58268(2013).
CC -!- SUBUNIT: Dimer of alpha and beta chains. A typical microtubule is a
CC hollow water-filled tube with an outer diameter of 25 nm and an inner
CC diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to
CC form protofilaments running lengthwise along the microtubule wall with
CC the beta-tubulin subunit facing the microtubule plus end conferring a
CC structural polarity. Microtubules usually have 13 protofilaments but
CC different protofilament numbers can be found in some organisms and
CC specialized cells. {ECO:0000256|ARBA:ARBA00011747}.
CC -!- SIMILARITY: Belongs to the tubulin family.
CC {ECO:0000256|ARBA:ARBA00009636}.
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DR EMBL; JX868519; AGA18194.1; -; Genomic_DNA.
DR AlphaFoldDB; M4ISH3; -.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR Gene3D; 3.40.50.1440; Tubulin/FtsZ, GTPase domain; 1.
DR InterPro; IPR002453; Beta_tubulin.
DR InterPro; IPR000217; Tubulin.
DR InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR PANTHER; PTHR11588; TUBULIN; 1.
DR PANTHER; PTHR11588:SF492; TUBULIN BETA-4 CHAIN; 1.
DR Pfam; PF00091; Tubulin; 1.
DR PRINTS; PR01163; BETATUBULIN.
DR PRINTS; PR01161; TUBULIN.
DR SMART; SM00864; Tubulin; 1.
DR SUPFAM; SSF52490; Tubulin nucleotide-binding domain-like; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 43..136
FT /note="Tubulin/FtsZ GTPase"
FT /evidence="ECO:0000259|SMART:SM00864"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AGA18194.1"
FT NON_TER 136
FT /evidence="ECO:0000313|EMBL:AGA18194.1"
SQ SEQUENCE 136 AA; 14718 MW; DA6018193A6EFBC1 CRC64;
VHLQTGQCGN QIGAAFWQQI SGEHGLDGNG VYNGTSDLQL ERMSVYFNEG ANNKYVPRAV
LVDLEPGTMD AVRAGPFGQL FRPDNFVFGQ SGAGNNWAKG HYTEGAELVD NVLDVVRREA
EGCDCLQGFQ ITHSLG
//
