ID M4N5Z1_TOBAC Unreviewed; 610 AA.
AC M4N5Z1;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Auxin efflux carrier component {ECO:0000256|RuleBase:RU362108};
GN Name=PIN1T {ECO:0000313|EMBL:AGG79239.1};
GN Synonyms=LOC107775627 {ECO:0000313|RefSeq:XP_016450863.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|EMBL:AGG79239.1};
RN [1] {ECO:0000313|EMBL:AGG79239.1}
RP NUCLEOTIDE SEQUENCE.
RA Muller K., Petrasek J.;
RT "PIN genes in tobacco.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [3] {ECO:0000313|RefSeq:XP_016450863.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May act as a component of the auxin efflux carrier.
CC {ECO:0000256|RuleBase:RU362108}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362108}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362108}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC {ECO:0000256|ARBA:ARBA00009177, ECO:0000256|RuleBase:RU362108}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362108}.
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DR EMBL; KC347302; AGG79239.1; -; Genomic_DNA.
DR RefSeq; XP_016450863.1; XM_016595377.1.
DR STRING; 4097.M4N5Z1; -.
DR PaxDb; 4097-M4N5Z1; -.
DR GeneID; 107775627; -.
DR KEGG; nta:107775627; -.
DR OMA; NDNQYVE; -.
DR OrthoDB; 405852at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0010329; F:auxin efflux transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0010315; P:auxin export across the plasma membrane; IBA:GO_Central.
DR GO; GO:0009926; P:auxin polar transport; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-UniRule.
DR InterPro; IPR014024; Auxin_eff_plant.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR NCBIfam; TIGR00946; 2a69; 1.
DR PANTHER; PTHR31752:SF59; AUXIN EFFLUX CARRIER COMPONENT 1; 1.
DR PANTHER; PTHR31752; AUXIN EFFLUX CARRIER COMPONENT 1B-RELATED; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294,
KW ECO:0000256|RuleBase:RU362108};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362108};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362108};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362108}; Transport {ECO:0000256|RuleBase:RU362108}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 102..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 491..516
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 528..549
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 555..576
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 588..607
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT REGION 213..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 66813 MW; 265CD48CC45A6C23 CRC64;
MITLSDFYHV MTAVVPLYVA MILAYGSVKW WKIFSPDQCS GINRFVALFA VPLLSFHFIA
GNNPYTMNIR FIAADTLQKL IVLGALAIWA NFSKRGSLEW SITLFSLSTL PNTLVMGIPL
LKGMYGDFSG SLMVQIVVLQ CIIWYTLMLF MFEFRGARML ISEQFPDTAG SIVSIHVDSD
VMSLDGRQVL ETEAEVKEDG KLHVTVRKSN ASRSDIFSRR SQGFSSTTPR PSNLTNAEIY
SLQSSRNPTP RGSSFNHTDF YSMVAGGRNS NFGANDVYGM SASRGPTPRP SNYEEESGKS
RFNYNHGAAA QQSSNNNNNT THYPAPNPGM FSPSNGAKAV ASTNNKKGNK GEEGGKDLHM
FVWSSSASPV SDVFGGHDYG ANLDQTAAKD VRVPISPGKV EGQRNNQENY MERDDFSFAN
RDAEMNINNQ EGEKVGENKA KVMPPTSVMT RLILIMVWRK LIRNPNTYSS LFGLTWSLVS
FRWNLKMPAI IAQSISILSD AGLGMAMFSL GLFMALQPRI IACGNSTAAF AMAVRFLTGP
AVMAASSIAV GLRGVLLHVA IVQAALPQGI VPFVFAKEYN VHPDILSTGV IFGMLIALPI
TLVYYILMGL
//
