ID   M4Q6K1_9BACT            Unreviewed;       144 AA.
AC   M4Q6K1;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE            EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
DE   Flags: Fragment;
GN   Name=bla {ECO:0000313|EMBL:AGH19649.1};
OS   uncultured soil bacterium.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=164851 {ECO:0000313|EMBL:AGH19649.1};
RN   [1] {ECO:0000313|EMBL:AGH19649.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Arjun J.K., Aneesh B., Bijoynandan S., Harikrishnan K.;
RT   "Prevalance of beta-lactam resistance genes in Arctic soil.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC         Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC         ChEBI:CHEBI:140347; EC=3.5.2.6;
CC         Evidence={ECO:0000256|ARBA:ARBA00001526};
CC   -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC       {ECO:0000256|ARBA:ARBA00009009}.
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DR   EMBL; KC428420; AGH19649.1; -; Genomic_DNA.
DR   AlphaFoldDB; M4Q6K1; -.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR045155; Beta-lactam_cat.
DR   InterPro; IPR000871; Beta-lactam_class-A.
DR   PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR   PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13354; Beta-lactamase2; 1.
DR   PRINTS; PR00118; BLACTAMASEA.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   3: Inferred from homology;
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251}.
FT   DOMAIN          4..138
FT                   /note="Beta-lactamase class A catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF13354"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AGH19649.1"
FT   NON_TER         144
FT                   /evidence="ECO:0000313|EMBL:AGH19649.1"
SQ   SEQUENCE   144 AA;  16069 MW;  004219C90100114C CRC64;
     LCGAVLSRID AGQEQLGRRI HYSQNDLVEY SPVTEKHLTD GMTVRELCSA AITMSDNTAA
     NLLLTTIGGP KELTAFLHNM GDHVTRLDRW EPELNEAIPN DERDTTMPVA MATTLRKLLT
     GELLTLASRQ QLIDWMEGIK LQDH
//