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Database: UniProt
Entry: M4R871_BIBTR
LinkDB: M4R871_BIBTR
Original site: M4R871_BIBTR 
ID   M4R871_BIBTR            Unreviewed;       405 AA.
AC   M4R871;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   25-OCT-2017, entry version 39.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=WQG_20890 {ECO:0000313|EMBL:AGH39366.1};
OS   Bibersteinia trehalosi USDA-ARS-USMARC-192.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Bibersteinia.
OX   NCBI_TaxID=1171377 {ECO:0000313|EMBL:AGH39366.1, ECO:0000313|Proteomes:UP000011846};
RN   [1] {ECO:0000313|EMBL:AGH39366.1, ECO:0000313|Proteomes:UP000011846}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=192 {ECO:0000313|Proteomes:UP000011846};
RA   Harhay G.P., Koren S., Phillippy A., McVey D.S., Kuszak J.,
RA   Clawson M., Harhay D.M., Heaton M., Chitko-Mckown C., Smith T.P.L.;
RT   "Annotation of the Bibersteinia trehalsoi USDA-ARS-USMARC-192 complete
RT   genome.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP003745; AGH39366.1; -; Genomic_DNA.
DR   EnsemblBacteria; AGH39366; AGH39366; WQG_20890.
DR   KEGG; bto:WQG_20890; -.
DR   PATRIC; fig|1171377.3.peg.2075; -.
DR   KO; K02313; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000011846; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011846};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011846}.
FT   DOMAIN       93    224       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      314    382       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     101    108       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   405 AA;  45823 MW;  32E6BC61C31DC90F CRC64;
     MANWVKESFL GEIQDLARYL SQDPTLSVIV KDRFDVEEKP AVVSARAPQE PEVSQIRTNL
     NSTLTFDNFV QGNSNQLAKA IAQQVANNPG RNTYNPFSLY GSTGLGKTHL LHAIGNEILK
     QNPSAKVLYI QAESFTRAMV SALQSNKMEN FKKFYRSIDV LMVDDIQFFA KKEGSQEEFF
     HTFNSLLEQD KQIIVASDVF PKNIENIEER MRSRLSWGIS AAIEPPELET RVAILMKKVE
     NQAAEFLATY GFPLELREDA AFFLAQKMRT NVRELEGALN SVIATSGFTR RPITVDFVRE
     ALKDRFAAYD SLITIENIQR TVAEYYNIKV ADLKSKSRSR SVARPRQMAM ALAKELTTHS
     LPEIGREFGR DHTTVIHACK TINELCAEDS SIQEDYTNLT RKLSS
//
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