ID M4RGR9_9BIFI Unreviewed; 866 AA.
AC M4RGR9;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:AGH41379.1};
GN ORFNames=D805_1112 {ECO:0000313|EMBL:AGH41379.1};
OS Bifidobacterium thermophilum RBL67.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1254439 {ECO:0000313|EMBL:AGH41379.1, ECO:0000313|Proteomes:UP000011835};
RN [1] {ECO:0000313|EMBL:AGH41379.1, ECO:0000313|Proteomes:UP000011835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RBL67 {ECO:0000313|EMBL:AGH41379.1,
RC ECO:0000313|Proteomes:UP000011835};
RX PubMed=23640377;
RA Jans C., Lacroix C., Follador R., Stevens M.J.;
RT "Complete Genome Sequence of the Probiotic Bifidobacterium thermophilum
RT Strain RBL67.";
RL Genome Announc. 1:E00191-13(2013).
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|ARBA:ARBA00008708}.
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DR EMBL; CP004346; AGH41379.1; -; Genomic_DNA.
DR RefSeq; WP_015450637.1; NC_020546.1.
DR AlphaFoldDB; M4RGR9; -.
DR KEGG; btp:D805_1112; -.
DR PATRIC; fig|1254439.12.peg.1105; -.
DR eggNOG; COG4581; Bacteria.
DR HOGENOM; CLU_017075_0_0_11; -.
DR Proteomes; UP000011835; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17921; DEXHc_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR021904; DUF3516.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF1; ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF12029; DUF3516; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AGH41379.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 61..217
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 259..426
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 866 AA; 96741 MW; 0D7D4F989324EFB1 CRC64;
MTQDEQRLEA DGTNGYGSLG VLAPHDGERR NLDADAIFDR FFGWVEDTKG ITPWPHQEEA
IMDLLSGDHV ILNTPTGSGK SLVALGMHFA ALCTGRRSYY TAPIKALVSE KFFDLVEVFG
RENVGMITGD THINADAPII CCTAEILANQ ALREGDQADI GCVAMDEFHY YGDSERGWAW
QVPLITLPRT QFLLMSATLG NVDAIADRLE DATDTDVDII ADAPRPVPLT YEYTDKPLPA
TIELLVGKGD TPIYIVHFSQ DAALTTAQAL ANSNVSTKEQ RQAIAEAMKG TKFTTAFGKI
LQRLLRTGVG VHHAGMLPRY RRLVEQLAQQ GLLPVICGTD TLGVGINVPI HSVVLTALTK
FDGVKTRRLR AREFHQIAGR AGRMGFDTEG LVVAEAPEYE IENAHQLAKA GNDPKKLKKV
KRKKPPEGFV TWNEHTFDKL IEAAPETLVP HLKITHSMVL NEVAQGGDAR ARVDKLIDDS
AQSDEQKAHL HQLADDIFRT MLDEHFIEAV PRDDDTTDYV LDVDMPDDFA LDQPLSPFLV
AALDLLDPDS PTYALDVISM VEATLDDPMP VLKAQQRQAR DKAMQEMKAD DIDYDERMER
LQEITYPKPL EDLLNQAFDT YRQSVPWAGD YMLSPKSVLR DMVETASDFN GYIARYNIAR
CEGTLLRYLS DAYRSLARTV PQDMLDDQLR DVISWLRLVV RSVDSSLVDE WEHAGQNDES
ALDATAPGDR DAVVSDRRGL TVLIRNAMFR RIQLMDLDRP EMLGDLDHDW GYGVHEWEDA
LEDYYDEHDY VGIDAAARSP EFFIIDDANE RKEHTWRVRQ IIDDSDGDHD WAIGGTVDLD
ATQETGETVF VDYHVGPIGS DGQIED
//
