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Database: UniProt
Entry: M4U0N8_9GAMM
LinkDB: M4U0N8_9GAMM
Original site: M4U0N8_9GAMM 
ID   M4U0N8_9GAMM            Unreviewed;       457 AA.
AC   M4U0N8;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   25-OCT-2017, entry version 38.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=PCNPT3_00005 {ECO:0000313|EMBL:AGH79943.1};
OS   Psychromonas sp. CNPT3.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Psychromonadaceae; Psychromonas.
OX   NCBI_TaxID=314282 {ECO:0000313|EMBL:AGH79943.1, ECO:0000313|Proteomes:UP000010320};
RN   [1] {ECO:0000313|EMBL:AGH79943.1, ECO:0000313|Proteomes:UP000010320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CNPT3 {ECO:0000313|EMBL:AGH79943.1,
RC   ECO:0000313|Proteomes:UP000010320};
RA   Lauro F.M., Chastain R.A., Stratton T.K., Ferriera S., Johnson J.,
RA   Yayanos A.A., Bartlett D.H.;
RT   "The complete genome sequence of the deep-sea bacterium Psychromonas
RT   CNPT2.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP004404; AGH79943.1; -; Genomic_DNA.
DR   RefSeq; WP_015463825.1; NC_020802.1.
DR   STRING; 314282.PCNPT3_01055; -.
DR   EnsemblBacteria; AGH79943; AGH79943; PCNPT3_00005.
DR   KEGG; psy:PCNPT3_00005; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000010320; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000010320};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010320}.
FT   DOMAIN      153    279       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      365    434       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     161    168       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      427    454       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   457 AA;  52017 MW;  9412538F0E1C38E0 CRC64;
     MSLAIWQECL AQLKDELSTG DFSTWLRPLQ AEYNNLILSL YSPNKFTSDW VRNNYMDIIE
     SKIQEISKLQ DPNLLIQIRL LVGNARPIEM QQKKPVHKPV SSAQPWDGEN KANKVAHKSN
     LIKKYTFDNF VEGKSNNFAI ATTQQIAENP GDVYNPLFLY AHPGLGKTHL LHAVGNAIVA
     ANPESKVVYI RSERFVQDMI NSIRNNTIEQ FKEYYASLDA LLIDDIHFFA GKDRSQEVLF
     QTFNSMLDAH QQVILTSDRF PKEIEGIDER LRTRFGWGLS IPIDPPELET RVAILITKAE
     ERGLVLPDDV AFFIAKRLTI TDVRVLEGAI ANISAKAQFT GQDITISLVQ DALRDMLAVH
     TRQTTIENIQ KIVAEHYRIK TSDMSSKRRT RTVARPRQIA MALAKELTQH SLPEIGEAFG
     GRDHTTVLHA CRKVAELRRE NNDIQEDYKI LIRTLSL
//
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