ID M5AFD0_9REOV Unreviewed; 304 AA.
AC M5AFD0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 03-MAY-2023, entry version 26.
DE SubName: Full=NSP3 protein {ECO:0000313|EMBL:BAN00235.1};
DE Flags: Fragment;
GN Name=NSP3 {ECO:0000313|EMBL:BAN00235.1};
OS Human rotavirus A.
OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC Reovirales; Sedoreoviridae; Rotavirus; Rotavirus A.
OX NCBI_TaxID=10941 {ECO:0000313|EMBL:BAN00235.1, ECO:0000313|Proteomes:UP000225573};
RN [1] {ECO:0000313|EMBL:BAN00235.1, ECO:0000313|Proteomes:UP000225573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RVA/Human-tc/MWI/OP2-506/1998/G8P[4]
RC {ECO:0000313|EMBL:BAN00235.1, ECO:0000313|Proteomes:UP000225573};
RX PubMed=23407423; DOI=10.1099/vir.0.050625-0;
RA Nakagomi T., Doan Y.H., Dove W., Ngwira B., Iturriza-Gomara M.,
RA Nakagomi O., Cunliffe N.A.;
RT "G8 rotaviruses with conserved genotype constellations detected in Malawi
RT over 10 years (1997-2007) display frequent gene reassortment among strains
RT co-circulating in humans.";
RL J. Gen. Virol. 94:1273-1295(2013).
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DR EMBL; AB753500; BAN00235.1; -; Genomic_RNA.
DR Proteomes; UP000225573; Genome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR CDD; cd20714; NSP3_rotavirus; 1.
DR Gene3D; 3.30.70.1610; -; 1.
DR Gene3D; 1.20.5.970; Nonstructural RNA-binding protein; 1.
DR Gene3D; 6.10.280.20; Rotavirus non-structural protein NSP3, N-terminal domain; 1.
DR HAMAP; MF_04094; ROTA_A_NSP3; 1.
DR HAMAP; MF_04090; ROTA_NSP3; 1.
DR InterPro; IPR042519; NSP3_N_rotavirus.
DR InterPro; IPR036082; NSP3_sf.
DR InterPro; IPR002873; Rotavirus_NSP3.
DR Pfam; PF01665; Rota_NSP3; 1.
DR SUPFAM; SSF69903; NSP3 homodimer; 1.
DR SUPFAM; SSF58030; Rotavirus nonstructural proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT COILED 158..210
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAN00235.1"
SQ SEQUENCE 304 AA; 35195 MW; 0CE455E4AE97BA85 CRC64;
MASSIINSSF EAAVVAATST LELMGIQYDY NEVYTRVKSK FDFVMDDSGV KNNLMGKAAT
IDQALNGKFS SSIRNRNWMT DSKTVARLDE GVNKLRLLLS SKGIDQKMRV LNACFSVKRV
PGKSSSVIKC TRLMKEKIER GEVEVDDTFV EERMEIDTID WKSRYDQLEK RFESLKQRVN
EKYTNWVIKA RKVNENMNSL QNVISQQQAH ISELQIYNNK LERDLQSKIG SVISSIEWYL
RSMELSDDIK SDIEQQLNSI DHINPVNAFD DFESILRNLI SDYDRIFIMF KGLLQQSNYT
YTYE
//
