ID M5BAG2_9MICO Unreviewed; 406 AA.
AC M5BAG2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Polyketide synthase III/chalcone synthase {ECO:0000313|EMBL:CCE75458.1};
DE EC=2.3.1.74 {ECO:0000313|EMBL:CCE75458.1};
GN Name=chsA {ECO:0000313|EMBL:CCE75458.1};
GN ORFNames=CMN_01510 {ECO:0000313|EMBL:CCE75458.1};
OS Clavibacter nebraskensis NCPPB 2581.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Clavibacter.
OX NCBI_TaxID=1097677 {ECO:0000313|EMBL:CCE75458.1, ECO:0000313|Proteomes:UP000012170};
RN [1] {ECO:0000313|EMBL:CCE75458.1, ECO:0000313|Proteomes:UP000012170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 2581 {ECO:0000313|Proteomes:UP000012170};
RA Gartemann K.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCE75458.1, ECO:0000313|Proteomes:UP000012170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 2581 {ECO:0000313|Proteomes:UP000012170};
RA Gartemann K.H., Blom J., Dreiseikelmann B., Fluegel M., Jaenicke S.,
RA Linke B., Sczcepanowski R., Wittmann J., Goesmann A., Puehler A.,
RA Eichenlaub R., Rueckert C.;
RT "The genome sequence of the maize-pathogen Clavibacter michiganensis subsp.
RT nebraskensis.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; HE614873; CCE75458.1; -; Genomic_DNA.
DR RefSeq; WP_015490215.1; NC_020891.1.
DR AlphaFoldDB; M5BAG2; -.
DR KEGG; cmc:CMN_01510; -.
DR HOGENOM; CLU_034992_0_2_11; -.
DR Proteomes; UP000012170; Chromosome.
DR GO; GO:0102128; F:chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016210; F:naringenin-chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:CCE75458.1};
KW Transferase {ECO:0000313|EMBL:CCE75458.1}.
FT DOMAIN 92..230
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 247..401
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 168
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 406 AA; 41873 MW; A6D5D851666381BB CRC64;
MIASIRSIAT ALPPTVLAQD GVRDLFGSQP ELGRLGTRLV SAAFNASGIR TRHTVIGELG
TAPGMAGADA PADAADGEPV FYDRTTGRIL TPGTGARNDT YIREAPALLL GAARQAVDEA
AGIEAADVTH VVTVSCTGFY APGPDYQVVR GLGLGASTHR FHLGFMGCYG AFPALRMAAQ
FCAADPDAVV LVVCVELCSL HLHSSDDADT IVASSVFGDG AAAAVVTARP APAGSTVLDL
EAFETVLTPV GEDDMAWTIG DQGFDMILSS YVPKIIDEHI TGALEPLWAQ VPALQGVAPA
AIEDWAIHPG GRSILDRVED RLALAPAQLE ASRSTLAEVG NMSSATVLFV LRRILHGTPP
ADVPGRPDVA EPAPIPASGP GAGRVCAMAF GPGLTVEAAL MTRRTI
//
