ID M5BTL3_THACB Unreviewed; 838 AA.
AC M5BTL3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Cell division control protein 25 {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN14_03866 {ECO:0000313|EMBL:CCO29845.1};
OS Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) (Lettuce bottom
OS rot fungus) (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=1108050 {ECO:0000313|EMBL:CCO29845.1, ECO:0000313|Proteomes:UP000012065};
RN [1] {ECO:0000313|EMBL:CCO29845.1, ECO:0000313|Proteomes:UP000012065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG1-IB / isolate 7/3/14 {ECO:0000313|Proteomes:UP000012065};
RX PubMed=23280342; DOI=10.1016/j.jbiotec.2012.12.010;
RA Wibberg D.W., Jelonek L.J., Rupp O.R., Hennig M.H., Eikmeyer F.E.,
RA Goesmann A.G., Hartmann A.H., Borriss R.B., Grosch R.G., Puehler A.P.,
RA Schlueter A.S.;
RT "Establishment and interpretation of the genome sequence of the
RT phytopathogenic fungus Rhizoctonia solani AG1-IB isolate 7/3/14.";
RL J. Biotechnol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO29845.1}.
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DR EMBL; CAOJ01005517; CCO29845.1; -; Genomic_DNA.
DR AlphaFoldDB; M5BTL3; -.
DR HOGENOM; CLU_002632_1_0_1; -.
DR Proteomes; UP000012065; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 2.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF99; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 4..64
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 261..395
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 454..683
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 96..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 750..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..702
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 838 AA; 92599 MW; FB96DD5B224EEA24 CRC64;
MASTNGFFAL VMHRYRAQDE TQLDIYPGRL VAVRRVEPSG WAGVVDVEGG RGWIPFRYVR
PIDDETVGIL EPIAQQLRLG AYRAVTTIRA TATDHLEGYS SPDSNESDAL GDEWANIPKQ
RRSSRAATRP RDLDSMKATP SGTPRVSLDE DLPVPTPTTA SGEKSPGVQF AAASPPTSFV
PSRVRAFKLR SRSKSRDGVR SDSESTTRPR RPSVSIRRTR VSMFGSPREP NPIEQIKRLD
SRPWYLKPVH SPATGDVVLD SDGSMRAGTL EAIVERLTCD APTRNHEITL RRDVLFTYEA
FTTSQHLFDL ITDQYSLEPP RELDESQFVD WKENKLRPTQ ARVLDVLGAW LDLPRLYQDD
PELIPRMCEF LQFVTKPESL ASEARRHLRT IEQLHQKELG SGLGRARSQR HASASYPRSE
SGQADSLYAV PSERSHSSHS HSSRHLPSAV NDLDPTALAH HLTLLESRLY MCIKRKQILE
WHKTSGLTDE SNANTNDLRN FCATSDRLAG WVKWSVLHMG SAVKRAEAVG AWIRVAEKCR
LLNNISSLAA IAAGLSSSDV SRLPYTWHLV PSARAQRLED LVLLTSPAGG FAQLKILYSN
IKFAVPFLGM YLTAIVHAAD QFKDYVPFLI SADRSPRDED GWATDGGHSE PVTPTQTQTR
TRSKSTRMSI GSPSPLSLNS VPPLNFSPNA SPSQSRRLPS EPPTPTLSIP PSSPTASMLG
SQTKLINFAK RHKQAEIIHA MLKFQDHPYT VSSRSEPQGS TSLPYPHSPS LSSSSSSSVT
LIASAGGVAW VEEQLTRAAK LTLGTDWTYD RSLRLYDDET GGRTGSAVDK ENMAAAGF
//
