ID M5CF64_THACB Unreviewed; 1071 AA.
AC M5CF64;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Peroxisomal ATPase PEX6 {ECO:0000256|ARBA:ARBA00034811};
DE AltName: Full=Peroxin-6 {ECO:0000256|ARBA:ARBA00034920};
GN Name=PEX6 {ECO:0000313|EMBL:CCO34592.1};
GN ORFNames=BN14_08696 {ECO:0000313|EMBL:CCO34592.1};
OS Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) (Lettuce bottom
OS rot fungus) (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=1108050 {ECO:0000313|EMBL:CCO34592.1, ECO:0000313|Proteomes:UP000012065};
RN [1] {ECO:0000313|EMBL:CCO34592.1, ECO:0000313|Proteomes:UP000012065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG1-IB / isolate 7/3/14 {ECO:0000313|Proteomes:UP000012065};
RX PubMed=23280342; DOI=10.1016/j.jbiotec.2012.12.010;
RA Wibberg D.W., Jelonek L.J., Rupp O.R., Hennig M.H., Eikmeyer F.E.,
RA Goesmann A.G., Hartmann A.H., Borriss R.B., Grosch R.G., Puehler A.P.,
RA Schlueter A.S.;
RT "Establishment and interpretation of the genome sequence of the
RT phytopathogenic fungus Rhizoctonia solani AG1-IB isolate 7/3/14.";
RL J. Biotechnol. 0:0-0(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00034440};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:13066;
CC Evidence={ECO:0000256|ARBA:ARBA00034440};
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Peroxisome membrane
CC {ECO:0000256|ARBA:ARBA00034691}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00034691}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00034691}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO34592.1}.
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DR EMBL; CAOJ01013354; CCO34592.1; -; Genomic_DNA.
DR AlphaFoldDB; M5CF64; -.
DR HOGENOM; CLU_000688_0_0_1; -.
DR Proteomes; UP000012065; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
DR CDD; cd19527; RecA-like_PEX6_r2; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047533; RecA-like_PEX6_r2.
DR PANTHER; PTHR23077; AAA-FAMILY ATPASE; 1.
DR PANTHER; PTHR23077:SF9; PEROXISOME ASSEMBLY FACTOR 2; 1.
DR Pfam; PF00004; AAA; 2.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00674; AAA; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Peroxisome biogenesis {ECO:0000256|ARBA:ARBA00022593}.
FT DOMAIN 765..906
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 126..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1036..1071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1055..1071
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1071 AA; 115181 MW; 94D8838B8B7DDF73 CRC64;
MRAHVLGLSE VDVELSKDIW DKLFPESKRR ASVVTLGRVE WARLNEDLGA GSCLLPFNTP
STNVDIVPTT PIPLSTVFVS AQAYAQSPDT YYEHILREGE LSVLATEPVL QGISVRDYTQ
FVLVPTTGSE SDSQSTSTSD VSESIPTSES DALEIDEDFL RGWDSTAHSP LALTPVPTRG
IDGHSVNVST YDLAKLGMLS GDWAILSPGE SHADRARLVQ VNAKDETTRS TIQVSPVLLF
NTIPPAYTSK SIDSNEPPSN KLFLRPTSYS SAAPPVPLAR SITLARVASK SANDKRLADR
VVRALRETLQ GAADNQNKRP PLLLKLNDLI AIHIDGSEPD AEDYDAEEEE SQGDAQKAIP
EVELDVEPPS VRSSSTEEGV DESTPIFLKV VNIDYAPTSL TNGSSDHSGD RNPSPDRTTT
AIAFGELGCS INPGSTRVSM VGVEHGLVPC MAPYEEDDED GDVESVLTPL LRATLLPNAA
HYGIALSALV RGARGSGKAR SVRRSAEKIG VGINAYTLIA DTEAKTEGLV RVRFEQAALC
APCVFLIRHI EALVRPGQGG KEPAMAAVLA ECIRGLGAAW GSTGYPVAVV ATTAEPDAIP
VGVMACFRHE IVLEAPDERR RLRMLNTIVA GQKLPLAADV ELSAVARETA ALHAGDLVHL
VRGARDQALK RVLKELSDIK SKPDSSIPIP TTRDLALAVI PITARDFELA LDGARAAYSE
SIGAPKIPNV SWDDVGGLAH VKGEILDTIQ LPLEHPELFA DGMKKRSGIL LYGPPGTGKT
LLAKAVATSC ALNFLSVKGP ELLNMYIGES EANVRRVFQR ARDARPCVVF FDELDSIAPR
RGQAGDSGGV MDRIVSQILA ELDGMGAGGN GGEVFVIGAT NRPDLLDPAL LRPGRFDRML
YLGVSKTHED QLRILQALTR KFKLDPSLEL AAVAERCPFN YTGADFYALC SDAMLKSMAR
KAEEIERRVA EINAAPPLPE HSYPMTAQYY LAELATPTET DVLVDQGDFE RALAELVPSV
SASELEHYRE VQQKFASSTI NSIEKEDSGD GADDEQEVDL PKLDKGKGKA A
//
