ID M5DQK8_9GAMM Unreviewed; 752 AA.
AC M5DQK8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=ATP-binding protease component ClpA {ECO:0000313|EMBL:CCU72215.1};
GN ORFNames=TOL_1795 {ECO:0000313|EMBL:CCU72215.1};
OS Thalassolituus oleivorans MIL-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Thalassolituus.
OX NCBI_TaxID=1298593 {ECO:0000313|EMBL:CCU72215.1, ECO:0000313|Proteomes:UP000011866};
RN [1] {ECO:0000313|EMBL:CCU72215.1, ECO:0000313|Proteomes:UP000011866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIL-1 {ECO:0000313|EMBL:CCU72215.1,
RC ECO:0000313|Proteomes:UP000011866};
RX PubMed=23599290; DOI=10.1128/genomeA.00141-13;
RA Golyshin P.N., Werner J., Chernikova T.N., Tran H., Ferrer M.,
RA Yakimov M.M., Teeling H., Golyshina O.V.;
RT "Genome Sequence of Thalassolituus oleivorans MIL-1 (DSM 14913T).";
RL Genome Announc. 1:1-3(2013).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
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DR EMBL; HF680312; CCU72215.1; -; Genomic_DNA.
DR RefSeq; WP_015486941.1; NC_020888.1.
DR AlphaFoldDB; M5DQK8; -.
DR STRING; 187493.CN03_09325; -.
DR KEGG; tol:TOL_1795; -.
DR PATRIC; fig|1298593.3.peg.1720; -.
DR eggNOG; COG0542; Bacteria.
DR HOGENOM; CLU_005070_4_2_6; -.
DR Proteomes; UP000011866; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:CCU72215.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:CCU72215.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011866};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..148
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 144..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 82890 MW; CB08461E4A245BFC CRC64;
MLNRELEHTL NEAFKEARSK RHEFMTVEHL LLALLDNDAA AAVLQACGAD VLKLRKDLEE
FVESTTPLIP EADGERETQP TLGFQRVLQR AVFHVQSSGK TEVTGANVLV AIFSEQESQA
VYFLKQQNIA RIDVVNYISH GISKVSGPEE SSDQMSENGD DEGESAGKSA LEGYAANLNR
QAREGKIDPL IGRDMEVNRL VQILARRRKN NPLLVGDSGV GKTAIVEGLA KRIVDGDVPE
VIQDAVVYSL DMGALLAGTK YRGDFEKRFK ALLAELKKQP HGILFIDEIH TIIGAGAASG
GVMDASNLLK PLLSSGEIRC VGSTTFTEFR GIFEKDSALT RRFQKIDVAQ PSVEDTYKIL
KGLKPKFEEH HNLRYTDKAL KAAAELADRY INDRNMPDKA IDVIDEAGAL QQLLPASRRK
KVIGVAEVEQ VVAAIARIPP KSVSSSDKEL LFKLEDKLQM VVFGQDEAIQ TLSTAIKMSR
AGLSAPQKPI GSFLFAGPTG VGKTEVTRQL ASVMGMELVR FDMSEYMERH TVSRLIGAPP
GYVGYDQGGL LTEAVNKNPH CVLLLDEIEK AHPEVFNILL QVMDHGTLTD NNGRKTDFRN
VILIMTTNAG ADRMSRASIG FTHQDHSVDG AEELKKFFTP EFRNRIDNII QFAPLSRDTI
LHVVDKFLAE LQGQLDDKRV MLNVNNDARL WLAEHGYDEK MGARPMARLV QDKIKKPLAE
KILFGDLAQG GEVDIDVEDG ALVIEVPEAV PV
//
