ID M5DZQ4_9FIRM Unreviewed; 550 AA.
AC M5DZQ4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Diguanylate cyclase (GGDEF domain) {ECO:0000313|EMBL:CCU78625.1};
GN ORFNames=HSACCH_00768 {ECO:0000313|EMBL:CCU78625.1};
OS Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643.
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC Halanaerobium.
OX NCBI_TaxID=1293054 {ECO:0000313|EMBL:CCU78625.1, ECO:0000313|Proteomes:UP000012063};
RN [1] {ECO:0000313|Proteomes:UP000012063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6643 {ECO:0000313|Proteomes:UP000012063};
RX PubMed=23640197; DOI=10.1128/genomea.00187-13;
RA Kivisto A., Larjo A., Ciranna A., Santala V., Roos C., Karp M.;
RT "Genome Sequence of Halanaerobium saccharolyticum subsp. saccharolyticum
RT Strain DSM 6643T, a Halophilic Hydrogen-Producing Bacterium.";
RL Genome Announc. 1:217-225(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU78625.1}.
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DR EMBL; CAUI01000005; CCU78625.1; -; Genomic_DNA.
DR AlphaFoldDB; M5DZQ4; -.
DR STRING; 1293054.HSACCH_00768; -.
DR eggNOG; COG2984; Bacteria.
DR eggNOG; COG3706; Bacteria.
DR InParanoid; M5DZQ4; -.
DR Proteomes; UP000012063; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR007487; ABC_transpt-TYRBP-like.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF04392; ABC_sub_bind; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000012063};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 343..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 424..550
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT COILED 365..396
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 550 AA; 64029 MW; 6BA954E2428E705E CRC64;
MGVIRIKPLI IILILIFLFM ILSSDVFAQK KILVLHSYHQ GLEWTDQISE GIRSVFPYND
KVKIFYEYLD AKRNYSEKYY DKLISLYREK AKIINFDVII VSDNAAFNFI LEYGEELYPK
TPIVFCGVNN FNSNFLVNKE DICGIVENAD HRKIIDLILK LHPNLNELII INDQTLTGKN
IQEELKVVLK DYKNKIEYEI WDTFTLNDLQ NRLISLDQND VIYLLVFNRD RAGNFISYNQ
GIDIIKSVSK NPIYGAWDFY LGKGILGGKL ISAQAQGKEA ALMAKKIING QQDFREKIVF
DKGSNFYFDY LELKKYNITE NDLPAGSRIV NQPDSFFKKN NRYLLWGLAF LIFIILILII
IYYLKNKEKE KLDKLNLELE QKVKQRTREL EKMTITDELT DLFNRRHILD LLEIEIKKAS
RYNRNLSVIM IDIDFFKKVN DNHGHQFGDK VLKILSDILQ QNTRNIDFVG RYGGEEFLII
LPETDLDQAY LVAEKLRKTV KETQISGLES GITISCGAAQ FEDDLGHQLI KRADDLLYKA
KAKGRDRVEI
//
