ID   M5E327_9FIRM            Unreviewed;       356 AA.
AC   M5E327;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=Arsenical resistance operon repressor {ECO:0000313|EMBL:CCU80590.1};
GN   ORFNames=HSACCH_02153 {ECO:0000313|EMBL:CCU80590.1};
OS   Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643.
OC   Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC   Halanaerobium.
OX   NCBI_TaxID=1293054 {ECO:0000313|EMBL:CCU80590.1, ECO:0000313|Proteomes:UP000012063};
RN   [1] {ECO:0000313|Proteomes:UP000012063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6643 {ECO:0000313|Proteomes:UP000012063};
RX   PubMed=23640197; DOI=10.1128/genomea.00187-13;
RA   Kivisto A., Larjo A., Ciranna A., Santala V., Roos C., Karp M.;
RT   "Genome Sequence of Halanaerobium saccharolyticum subsp. saccharolyticum
RT   Strain DSM 6643T, a Halophilic Hydrogen-Producing Bacterium.";
RL   Genome Announc. 1:217-225(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCU80590.1}.
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DR   EMBL; CAUI01000023; CCU80590.1; -; Genomic_DNA.
DR   RefSeq; WP_005489856.1; NZ_CAUI01000023.1.
DR   AlphaFoldDB; M5E327; -.
DR   STRING; 1293054.HSACCH_02153; -.
DR   eggNOG; COG0640; Bacteria.
DR   InParanoid; M5E327; -.
DR   OrthoDB; 9798835at2; -.
DR   Proteomes; UP000012063; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; NF033788; HTH_metalloreg; 1.
DR   PANTHER; PTHR33154:SF18; ARSENICAL RESISTANCE OPERON REPRESSOR; 1.
DR   PANTHER; PTHR33154; TRANSCRIPTIONAL REGULATOR, ARSR FAMILY; 1.
DR   Pfam; PF01022; HTH_5; 1.
DR   PRINTS; PR00778; HTHARSR.
DR   SMART; SM00418; HTH_ARSR; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50987; HTH_ARSR_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000012063}.
FT   DOMAIN          265..356
FT                   /note="HTH arsR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50987"
SQ   SEQUENCE   356 AA;  41645 MW;  6EC1F8C585FA233B CRC64;
     MSSKNYKLDK SVIYELFLSL FRLKNDKIIK LEDLELKKEI KLDKEIVNWA AETMVKIPQS
     KREMIAKYFN EESYFGLCLI SEIPKLEVEN IEDYLQHLKE KEAVDFLKKF TESGYGPSSS
     EKLDLLKVKS LIANEKKAAK FVNEKLNFSS AQKWNLLQFY FEPEAMKNEF IELLEWYYKN
     IFSSDLDWIK DKLENINDNY QENLNRYGTK YLENILSKLI DDPLAGEQNY IAFSYFYETR
     ILNSTLDNGD SFYLIGFRFP EIFAADEEGL LGSLEIFKAL ADETRLNIIS LLAEKTMYGN
     ELAEQLNLTN ATISHHVSKL LMNNIIQAQK ENNKLYFKLN KNKFKTAVLK AVNNLI
//