ID M5FX76_DACPD Unreviewed; 509 AA.
AC M5FX76;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Phosphomethylpyrimidine kinase {ECO:0000313|EMBL:EJU02586.1};
GN ORFNames=DACRYDRAFT_21647 {ECO:0000313|EMBL:EJU02586.1};
OS Dacryopinax primogenitus (strain DJM 731) (Brown rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Dacrymycetes;
OC Dacrymycetales; Dacrymycetaceae; Dacryopinax.
OX NCBI_TaxID=1858805 {ECO:0000313|EMBL:EJU02586.1, ECO:0000313|Proteomes:UP000030653};
RN [1] {ECO:0000313|EMBL:EJU02586.1, ECO:0000313|Proteomes:UP000030653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DJM-731 SS1 {ECO:0000313|EMBL:EJU02586.1,
RC ECO:0000313|Proteomes:UP000030653};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
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DR EMBL; JH795861; EJU02586.1; -; Genomic_DNA.
DR AlphaFoldDB; M5FX76; -.
DR STRING; 1858805.M5FX76; -.
DR HOGENOM; CLU_020520_2_1_1; -.
DR OMA; FWEMFPY; -.
DR OrthoDB; 5477821at2759; -.
DR Proteomes; UP000030653; Unassembled WGS sequence.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR CDD; cd19367; TenA_C_ScTHI20-like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR004305; Thiaminase-2/PQQC.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF03070; TENA_THI-4; 1.
DR SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EJU02586.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030653};
KW Transferase {ECO:0000313|EMBL:EJU02586.1}.
FT DOMAIN 16..270
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT DOMAIN 303..506
FT /note="Thiaminase-2/PQQC"
FT /evidence="ECO:0000259|Pfam:PF03070"
SQ SEQUENCE 509 AA; 55351 MW; DFD3D7129C897B90 CRC64;
MASPPPPKTL TIAGSDSGGG AGIQADLKTF TALGTYGLSV ITALTSQNTL GVDGVVAVNP
PFVSKQLRAV IDDIGVDTIK IGMLHNHHII EAVAETLTAL FPPAGSSKLP PIVLDPVMIS
TSEHVLLDPS SLPALKTHLL PLCTLVTPNI AEAKKLSSLE RIDSVEDMKA AAKKISELGS
HAVLVKGGHL DERQVYDVLY ETANGEYTVF EHPRIHTKNT HGTGCTQSSA IAAFLSKGNS
LREAIQLATD YVQAALLASF DIGHGSGPLN HLVAILPRAL AAPSDLDPHP FTSYLIRSCA
VDWTMYTRKH PFILGLKDGT LPRESFIHFL KQDYIFLTHY ARIHALAAYK SFSMEEIDAA
TDIVKHIVRE SKHHIAFCQS WGISLEEFHS TPESGHTVAY TRYVLDTGVS NSLLALRVAT
APCLLGYGDV GTWLHDDPGT KREGNAYWPW IEGYAGEDFQ KAVRKGRDLL EESVKANPLS
PAQLAEMVNI FRKATRLEVG FWEQSWSLQ
//
