ID M5GC74_DACPD Unreviewed; 681 AA.
AC M5GC74;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=RhoGAP-domain-containing protein {ECO:0000313|EMBL:EJU03697.1};
GN ORFNames=DACRYDRAFT_49844 {ECO:0000313|EMBL:EJU03697.1};
OS Dacryopinax primogenitus (strain DJM 731) (Brown rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Dacrymycetes;
OC Dacrymycetales; Dacrymycetaceae; Dacryopinax.
OX NCBI_TaxID=1858805 {ECO:0000313|EMBL:EJU03697.1, ECO:0000313|Proteomes:UP000030653};
RN [1] {ECO:0000313|EMBL:EJU03697.1, ECO:0000313|Proteomes:UP000030653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DJM-731 SS1 {ECO:0000313|EMBL:EJU03697.1,
RC ECO:0000313|Proteomes:UP000030653};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH795859; EJU03697.1; -; Genomic_DNA.
DR AlphaFoldDB; M5GC74; -.
DR STRING; 1858805.M5GC74; -.
DR HOGENOM; CLU_010730_1_0_1; -.
DR OMA; DSGWQAR; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000030653; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF134; ACTIVATING PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000030653}.
FT DOMAIN 110..405
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 475..673
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 205..253
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 7..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 75999 MW; 47890268F0F7505D CRC64;
MGLPASLTHT PTETTPVRTH SQEVVSPNLP AIPVLDRVSA QSRASPAPSP THTTSFHQSQ
PSADSTSYVQ TSRSSRLGHE RYPSQGIANG SSTITSSWPP QDEEPEIVPT GFDEGVLRAL
CELDCGVPLL LDRIKQGTVS CREVATFFKK RAALEEDYGR NLQKLSRLTG EQYSLSEGKA
GTFVNSWHSA MRIHEILAEN RIRFAMRLNE MSDELLNLAK EVEKNRKQSK ELSNRYERTL
QDAEVATDKA KARFDSNAEE LERLLVMKEG ETMKEAGITP RTGDRGGQSG KRVLGKAINK
GGMLLKGKNP ASLMRQEEDV RNRLTTSSDT YRKALLEAQH IRQEYFNFQL PRILRSLKEC
SDEVDLGTQY HLSRYAHLYE NTLLTDGQVL APVPHPDSTI DGAGIKDIME NIDSRGDFKV
YMQNYAIANS TPRGPRREGP PEEQYISFTP THATKPSSDK LTMSPEKISA TTFGVDLGEQ
MTRDNVEVPR ILERCAGAIE MHGLQSVGIY RLSGTTSRVN RLKASFDRGK YVETSLLDEE
ASTDVNIVSG ALKLWLRELP EPLFTHSLYP GFIEAAKIDN DRLRHIRLHE RVNDLPDANY
ATLKFLMGHL HKVQQHSDVN QMRISNLSIV FGPTLLGPPL GGMPGVESGA AITDHQWQSR
AVETILEHYL DIFVEDGEEV Q
//
