ID M5PE65_9BACI Unreviewed; 210 AA.
AC M5PE65;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Acetoin utilization protein AcuA {ECO:0000256|PIRNR:PIRNR021278};
DE EC=2.3.1.- {ECO:0000256|PIRNR:PIRNR021278};
DE AltName: Full=Protein acetyltransferase AcuA {ECO:0000256|PIRNR:PIRNR021278};
GN ORFNames=BSONL12_10127 {ECO:0000313|EMBL:EME75335.1};
OS Bacillus sonorensis L12.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1274524 {ECO:0000313|EMBL:EME75335.1, ECO:0000313|Proteomes:UP000011907};
RN [1] {ECO:0000313|EMBL:EME75335.1, ECO:0000313|Proteomes:UP000011907}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L12 {ECO:0000313|EMBL:EME75335.1,
RC ECO:0000313|Proteomes:UP000011907};
RX PubMed=23538904;
RA Adimpong D.B., Sorensen K.I., Nielsen D.S., Thorsen L., Rasmussen T.B.,
RA Derkx P.M., Jespersen L.;
RT "Draft Whole-Genome Sequence of Bacillus sonorensis Strain L12, a Source of
RT Nonribosomal Lipopeptides.";
RL Genome Announc. 1:E0009713-E0009713(2013).
CC -!- FUNCTION: Part of the acuABC operon, which is possibly involved in the
CC breakdown of acetoin and butanediol. Acts as an acetyltransferase
CC inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys
CC residue. {ECO:0000256|PIRNR:PIRNR021278}.
CC -!- PATHWAY: Ketone degradation; acetoin degradation.
CC {ECO:0000256|PIRNR:PIRNR021278}.
CC -!- SUBUNIT: Monomer. {ECO:0000256|PIRNR:PIRNR021278}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family.
CC {ECO:0000256|PIRNR:PIRNR021278}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EME75335.1}.
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DR EMBL; AOFM01000006; EME75335.1; -; Genomic_DNA.
DR RefSeq; WP_006638019.1; NZ_AOFM01000006.1.
DR AlphaFoldDB; M5PE65; -.
DR STRING; 1274524.BSONL12_10127; -.
DR GeneID; 79845623; -.
DR PATRIC; fig|1274524.3.peg.2193; -.
DR eggNOG; COG0454; Bacteria.
DR OrthoDB; 5416633at2; -.
DR UniPathway; UPA00040; -.
DR Proteomes; UP000011907; Unassembled WGS sequence.
DR GO; GO:0019152; F:acetoin dehydrogenase activity; IEA:InterPro.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR024699; AcuA.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR000182; GNAT_dom.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR PIRSF; PIRSF021278; AcuA; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51186; GNAT; 1.
PE 3: Inferred from homology;
KW Acetoin catabolism {ECO:0000256|PIRNR:PIRNR021278};
KW Acyltransferase {ECO:0000256|PIRNR:PIRNR021278};
KW Transferase {ECO:0000256|PIRNR:PIRNR021278}.
FT DOMAIN 19..189
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 210 AA; 24585 MW; 838453FA98D949C6 CRC64;
MEHHKTYHAK ELHTGEGTLL VEGPISPDKL ADYEFHAELT AFRPSQKQHE ALIEIAGLPE
GRIIIARFHH TIVGYVTYVY PDPLERWSEG NMENLIELGA IEVIPKFRGH SVGKTLLEVS
MMDKQMEKYI VITTEYYWHW DLKGTNKDVW EYRKMMEKMM NAGGLVWFAT DDPEISSHPA
NCLMARIGKE VSRESIERFD RLRFHNRFMY
//
