ID M5WR00_PRUPE Unreviewed; 587 AA.
AC M5WR00;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=PRUPE_3G092400 {ECO:0000313|EMBL:ONI16325.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI16325.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI16325.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX41 subfamily.
CC {ECO:0000256|ARBA:ARBA00023594}.
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DR EMBL; CM007653; ONI16325.1; -; Genomic_DNA.
DR RefSeq; XP_007215023.1; XM_007214961.1.
DR AlphaFoldDB; M5WR00; -.
DR SMR; M5WR00; -.
DR STRING; 3760.M5WR00; -.
DR EnsemblPlants; ONI16325; ONI16325; PRUPE_3G092400.
DR GeneID; 18782659; -.
DR Gramene; ONI16325; ONI16325; PRUPE_3G092400.
DR KEGG; pper:18782659; -.
DR eggNOG; KOG0341; Eukaryota.
DR HOGENOM; CLU_003041_16_5_1; -.
DR OMA; LGDERGC; -.
DR OrthoDB; 5487240at2759; -.
DR Proteomes; UP000006882; Chromosome g3.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd17951; DEADc_DDX41; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR044113; DEADc_DDX41.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR47958; ATP-DEPENDENT RNA HELICASE DBP3; 1.
DR PANTHER; PTHR47958:SF103; ATP-DEPENDENT RNA HELICASE DDX41-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 142..170
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 173..357
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 368..528
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 546..561
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
SQ SEQUENCE 587 AA; 65732 MW; 68EB6FA5422962BC CRC64;
MEEEDDYFEY VPVAKRRAME AQKILLRKGK SSGLEEDLEK SKLAEAKPSL LVKASQLKRE
APEITPAEQM VQQEKEMIEN LSDRKTLMSV RELAKGITYT DPIPTGWKSP LHIRRMPSKQ
CDLVRKQWHI IVSGEDVPPP IKNFKDMRFP EPILKMLKTK GIVQPTPIQV QGLPVILSGR
DMIGIAFTGS GKTLVFVLPL IMVALQEEIM MPIVPGEGPF GLIICPSREL ARQTYEVVEE
FLIPLREAGY PEIRPLLCIG GVDMRSQLEI VKKGVHIVVA TPGRLKDMLA KKKMNLNNCR
YLTLDEADRL VDLGFEDDIR EVFDHFKAQR QTLLFSATMP TKIQNFAKSA LVKPVLVNVG
RAGAANLDVI QEVEYVKQEA KIVYLLECLQ KTPPPVLIFC ENKADVDDIH EYLLLKGVEA
VAIHGGKDQE EREYAISSFK AGKKDVLVAT DVASKGLDFP DIQHVINYDM PPEIENYVHR
IGRTGRCGKT GIATTFINKN QTETTLLDLK HLLQEAKQRI PPVLAELNDP MEDVDAITDA
SGVKGCAYCG GLGHRIRDCP KLEHQKSMAI ASSRRDYFGS GGYRGEI
//
